ACTRN12624000772549
Not yet recruiting
Phase 1
A pilot study to evaluate the effectiveness of intranasal Botulinum Toxin Type A Spray for adult patients with Rhinitis
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Allergic Rhinitis
- Sponsor
- Metro North Hospital and Health Service
- Enrollment
- 15
- Status
- Not yet recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Patients greater than or equal to 18 years
- •2\. Clinically confirmed diagnosis of allergic or non\-allergic rhinitis.
- •3\. Prior Radioallergosorbent test (RAST) test and immunoglobulin E ( IgE) level (as part of the patient’s standardised medical treatment).
- •4\. Incomplete management of symptoms despite appropriate medical treatment (intra\-nasal corticosteroid and nasal douching)
Exclusion Criteria
- •1\. Patients less than 18 years
- •2\. Participants who are unable to provide informed consent.
- •3\. Participants who are pregnant, breast feeding or planning to become pregnant during study.
- •4\. Participants with an absolute contraindication to botulinum toxin type A specifically allergy, pregnancy, coexisting myasthenia gravis.
- •5\. Coexisting chronic rhinosinusitis.
- •6\. Subjects with known hypersensitivity or contraindications to mometasone nasal spray.
- •7\. Participants who have been on an active investigational therapy within 1 month prior to screening
- •8\. Women of childbearing potential who are not willing to use double barrier method of contraception during the study. That is:
- •\-Use of contraceptive pill or intrauterine device (IUD) or similar
- •\-and Condoms
Outcomes
Primary Outcomes
Not specified
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