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Instructed Home-based Physical Exercise for Patients With Liver Cirrhosis

Not Applicable
Recruiting
Conditions
Liver Cirrhosis
Registration Number
NCT05061576
Lead Sponsor
Karolinska University Hospital
Brief Summary

The study will compare two forms of advice regarding physical activity for patients hospitalized with cirrhosis that are preparing for leaving the hospital. One arm consists of current standard of care: simple oral advice on exercise. One arm instead gives patients a structured but simple paper template on physical activity.

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
100
Inclusion Criteria
  • Liver cirrhosis diagnosed with previous clinical assessment and radiology (de-formed liver, noduli, varices, collaterals, splenomegaly >12 cm) or with biopsy (fibrosis grade 4). ICD-code K70.3, K74.6.
  • MELD < 25
  • Understanding the Swedish language.
  • Signed informed consent.
Exclusion Criteria
  • Performance status ≥3.
  • Severe pain which prevents the patient to perform the physical activities, as judged by the attending physician at time of discharge.
  • Previously liver transplanted
  • Unlikely to be compliant to follow-up (living in other parts of Sweden), as judged by the attending physician at time of discharge.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Change in quality of life summary score, as measured with the CLDQ tool3 months

Change in quality of life, as measured with the CLDQ tool (gives a summary score between 1-7, a higher score suggests a better quality of life).

Secondary Outcome Measures
NameTimeMethod
Mortality3 months

Overall mortality

MELD3 months

Model of End-stage Liver Disease score (range 6-40, a higher score indicates a worse prognosis)

Frailty3 months

Frailty as measured with the Liver Frailty Index.

Trial Locations

Locations (1)

Karolinska University Hospital

🇸🇪

Stockholm, Sweden

Karolinska University Hospital
🇸🇪Stockholm, Sweden
Hannes Hagström, MD, PhD
Contact
0046858580000
hannes.hagstrom@ki.se

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