Comparison of clinical outcomes of Virtual Reality assisted rehabilitation with dose-matched conventional rehabilitation in patients with stroke

Phase 2

• Conditions: Recovery of post-stroke motor impairments in response to the Virtual Reality assisted rehabilitation; Nervous System Diseases

• Registration Number: ISRCTN17494358
• Lead Sponsor: Indian Council of Medical Research

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2024-02-15
• Last Update Posted: 27 February 2024
• Study Completion: 2027-03-30

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1. Age 18-75 years
2. Gender both male and female
3. Patients with stroke chronicity 3-120 months (The groups in 3month-2 years and 2-10 years will be evaluated post-hoc separately)
4. No previous clinical stroke
5. Single-lesioned, Ischemic / Hemorrhagic Cortical/Sub-cortical stroke type
6. Patient conscious, coherent, comprehendible, cooperative
7. Patient having upper-limb paresis
8. Mini-Mental State Examination (MMSE) score 24-30.
9. MRC power 1-3
10. Modified Ashworth Scale 1, 1+, 2, 3
11. Brunnstrom Stage 3-5
12. EMG activity of EDC muscle present (even if it is a flicker)
13. Surgical intervention to correct hand deformities e.g., tendon transfers with power quantified through surface EMG

Exclusion Criteria

1. Having progressive neurological disorders
2. Cognitively declining (MMSE < 24)
3. Clinically unstable
4. Contraindications to MRI and TMS procedure
5. Having Aphasia
6. Major stroke (NIHSS >16)

Study & Design

• Study Type: Interventional
• Study Design: Not specified