Implementation of first-trimester screening and prevention of preeclampsia

Phase 3

• Conditions: High-risk pregnancy for preterm-preeclampsia identified by screening at 11-13 weeks; preeclampsia

• Registration Number: JPRN-jRCTs041190035
• Lead Sponsor: Shiozaki Arihiro

Brief Summary

This Japan-only analysis shows that for pregnant women diagnosed as high-risk for preterm PE by screening at 11-13 weeks' gestation, low-dose aspirin administered as early as possible may delay the onset of early-onset PE by approximately 2 weeks and may also delay the onset of preterm-PE by delaying the onset of PE by approximately 4 weeks, which may result in a birth weight of approximately 200-300 g heavier. low-dose aspirin treatment may contribute to improving the prognosis of both.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-05-30
• Study Completion: 2022-10-01
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 5653

Inclusion Criteria

Singleton pregnancy

Exclusion Criteria

Multiple pregnancy, Major fetal defects identified at 11-13 weeks of assessment, Non-viable fetus

Study & Design

• Study Type: Interventional
• Study Design: Not specified