The establishment and research on the optimization of clinical rehabilitation plan and the evaluation system of rehabilitation outcome of traditional Chinese medicine for knee osteoarthritis

Not Applicable

Recruiting

• Conditions: Osteoarthritis of knee

• Registration Number: ITMCTR2000003352
• Lead Sponsor: Wangjing Hospital, Chinese Academy of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Male
• Target Recruitment: Not specified

Inclusion Criteria

1. It is in accordance with the diagnostic standard of knee osteoarthritis;
2. According to Kellgren - Lawrance (K-L), the radiology diagnosis was classified as grade II or grade III. (grading standard of K-L: grade 0, completely normal; grade I, joint space is suspected to be narrow, and there may be osteophyte; grade II, obvious osteophyte, joint space is normal or suspected to be narrow; grade III, moderate osteophyte, joint space is clear and narrow, subchondral bone is partially sclerotic; grade IV, giant osteophyte, joint space is obviously narrow, subchondral bone is severely sclerotic, and deformity is clear);
3. Aged 50-80 years;
4. Volunteer and sign informed consent.

Exclusion Criteria

1. Patients with knee joint disease, such as psoriasis, syphilitic neuropathy, Charcot's disease, brown yellow disease, metabolic osteopathy, acute trauma, etc., with cardiovascular, cerebrovascular, liver, kidney, hematopoietic system, endocrine system and other serious primary diseases and psychosis, secondary or traumatic knee osteoarthritis;
2. Participants in other clinical trials affecting the evaluation of the results of this study;
3. In the past 3 months, the patients had received intraarticular steroid injection or arthroplasty; in the past 6 months, the patients had received intraarticular hyaluronic acid injection; in one year, they were ready for total knee arthroplasty;
4. Unable to walk independently, need to rely on auxiliary equipment such as walking stick to walk;
5. Those who are unable to cooperate with assessment, treatment and testing for other reasons.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
WOMAC;visual analogue scale, VAS;Knee Outcome Survey Activities of Daily Living Scale, KOS-ADLS;

Secondary Outcome Measures

Name	Time	Method
6-minute walk test;ime up and go test, TUG;Stair test;Passive mobility of knee joint;Active mobility of knee joint;