The Effect of Low-Level Laser Therapy on Patient's Pain and Healing of Palatal Donor Site Following Free Gingival Graft: A Randomized Controlled Clinical Trial
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Gingival Recession
- Sponsor
- Tehran University of Medical Sciences
- Enrollment
- 12
- Locations
- 1
- Primary Endpoint
- degree of epithelialization
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
The aim of this randomized split-mouth design clinical trial is to clinically evaluate the effectiveness of diode laser in the healing of donor site of palate in free gingival graft.
Detailed Description
Free gingival graft is the most predictable and successful method for increasing the width of keratinized tissue around teeth/dental implants and vestibular deepening. However, patient discomfort during the healing time is a major disadvantage of this procedure. Several methods have been introduced to accelerate the healing time and reduction of patient's pain during first days after surgery. Low-level lasers have shown promising results in biostimulation of cell growth and differentiation in cultures. However, there are lack of well designed double blind placebo controlled randomized controlled clinical studies evaluating the effects of Low-level laser therapy in acceleration of wound healing and pain relief of patients undergoing free gingival grafts.
Investigators
Neda Moslemi
Assistant Professor
Tehran University of Medical Sciences
Eligibility Criteria
Inclusion Criteria
- •lack of keratinized tissue around teeth (bilateral)
Exclusion Criteria
- •patients with systemic diseases
- •non-cooperative patients
- •poor oral hygiene
- •root surface restorations or active caries
Outcomes
Primary Outcomes
degree of epithelialization
Time Frame: At day 21
3% hydrogen peroxide (H2O2) was applied to the wound by a sterile gause to see the bubbling * Complete epithelialization: bubble was not seen * Partial epithelialization: bubbles were seen in lesser than half of donor site * No epithelialization: bubble were seen in more than half of donor site
Secondary Outcomes
- Visual analogue scale (VAS) pain score(at day 14)
- Clinical healing(at day 21)