Effect of hydroalcoholic extract of Ruscus hyrcanus in treatment of chronic venous insufficiency
Early Phase 1
Recruiting
- Conditions
- Varicose vein of lower extremities.Asymptomatic varicose veins of lower extremities
- Registration Number
- IRCT20100107003014N21
- Lead Sponsor
- Sari University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
at least 18 years old
varicose grade C1, C2 and C3
Exclusion Criteria
History of allergic reactions to plants in this family
Pregnancy and Lactation
Uncontrolled Diabetes
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The amount of pain and feet heaviness according to the questionnaire. Timepoint: Completion of the questionnaire and examination at the beginning of the study and 14 and 28 days after the start of the application of Ruscus ointment. Method of measurement: Aberdeen varicose vein questionnaire (AVVQ), Observation and examination.;Changes in the amount of swollen ankles according to the questionnaire. Timepoint: Completion of the questionnaire and examination at the beginning of the study and 14 and 28 days after the start of the application of Ruscus ointment. Method of measurement: Aberdeen varicose vein questionnaire (AVVQ), Observation and examination.;Variation of vascular changes in vascular area according to questionnaire. Timepoint: Completion of the questionnaire and examination at the beginning of the study and 14 and 28 days after the start of the application of Ruscus ointment. Method of measurement: Aberdeen varicose vein questionnaire (AVVQ), Observation and examination.
- Secondary Outcome Measures
Name Time Method