Development of simple limbal epithelial transplantation for treatment of limbal stem cell deficiency in Thailand

ational Science and Technology Development Agency0 个研究点目标入组 30 人开始时间: 2017年6月9日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•1. Patients with unilateral or bilateral limbal stem cell deficiency (LSCD) from chemical or thermal burns, chronic keratitis, multiple corneal surgeries, and prolonged use of eye drops
•2. Patients with clinical signs of LSCD at least 180 degrees of the corneal circumference
•3. Patients diagnosed with LSCD by impression cytology

•1. Patients aged below 18 years
•2. Patients with severe dry eye (Schirmer's test = 0 mm)
•3. Patients with uncontrollable glaucoma
•4. HIV-infected patients
•5. Patients with hepatitis C virus infection
•6. Patients with ongoing ocular infection
•7. Patients with contraindications of ocular surgery or general anesthesia
•8. Patients with pregnancy
•9. Patients unable to follow-up
•10. Patients with non-compliance, physically or mentally
•Additional exclusion criteria for allo-SLET patients
•1. Patients with contraindications of immunosuppressive agents or sterioids e.g. uncontrollable diabetes mellitus, ongoing systemic infection, hepatic failure, renal failure, etc.
•2. Patients allergic to immunosuppressive agents or steroids

发起方

ational Science and Technology Development Agency