Calanus Oil Supplementation and Maximal Oxygen Uptake

Not Applicable

Completed

• Conditions: Healthy
• Interventions: Dietary Supplement: Calanus oil; Dietary Supplement: placebo dietary oil

• Registration Number: NCT02908828
• Lead Sponsor: Norwegian University of Science and Technology

Brief Summary

Copepod oil is extracted from the marine copepod Calanus finmarchicus, the dominant plankton species in the marine food web in the Norwegian Sea. Copepods constitute the largest renewable and harvestable resource in the Norwegian Sea and adjacent waters, and it is now developed knowledge and technology for sustainable harvesting of this "new" resource. The purpose of this study is to investigate whether Calanus copepod oil supplementation has an equivalent effect on maximal oxygen uptake in humans to that seen in experimental studies in mice.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2016-09-14
• Study First Submitted QC: 2016-09-17
• Study First Posted: 2016-09-21
• Study Start: 2016-10
• Primary Completion: 2017-09-19
• Study Completion: 2017-09-19
• Status Verified: 2020-09
• Last Update Submitted: 2020-09-29
• Last Update Posted: 2020-09-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 71

Inclusion Criteria

• in good health
• Body mass index (BMI) between 18,5 and 29,9

Exclusion Criteria

• Medical condition limiting VO2max (COPD or asthma).
• diagnosed coronary artery disease
• Any other significant medical condition
• medication effecting exercise capacity (e.i. betablockers)
• Pregnancy
• Participation in other clinical trials
• Shellfish allergies
• Systolic blood pressure > 170 mmHG, or diastolic BP > 105 mmHG.
• contraindications for maximal exercise testing

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Calanus oil	Calanus oil	4 capsules of 500 mg Calanus oil once every day
Placebo	placebo dietary oil	4 capsules of 500 mg dietary oil once every day

Primary Outcome Measures

Name	Time	Method
maximal oxygen uptake (VO2max)	6 months	Measured with indirect calorimetry at a treadmill (running/walking) with gradually increasing work load until exhaustion. After 10-15 min with warmup at 70% of maximal heart rate, work load will be increased every 1-2 minute and the changes maximal oxygen uptake (VO2) will be recorded automatically.

Secondary Outcome Measures

Name	Time	Method
Self-reported physical activity	6 months	assessed with International Physical Activity Questionnaire (IPAQ) short version
Body composition (InBody, Japan)	6 months

Trial Locations

Locations (2)

Institutt for Medisinsk Biologi, UiT Norges arktiske universitet; 🇳🇴 Tromsø, Norway

KG Jebsen-senter for Hjertetrening, NTNU; 🇳🇴 Trondheim, Norway