Impact of Total Thyroidectomy on Voice and Swallowing

• Conditions: Thyroidectomy; Voice Alteration; Swallowing Alteration
• Interventions: Other: Endoscopy of larynx; Other: Voice Handicap Index; Other: Swallowing Assesment

• Registration Number: NCT01607242
• Lead Sponsor: University of Thessaly

Brief Summary

Purpose of this study is to evaluate the outcome of total thyroidectomy on vocal and swallowing function.

Detailed Description

Voice and swallowing alterations are frequently reported after thyroidectomy, even in the absence of nerve injury. These impair quality of life.

Purpose of this study is to evaluate the outcome of total thyroidectomy on vocal and swallowing function.

Patients will be assessed using the Greek- version of Voice Handicap Index (VHI) and a questionnaire developed by the authors regarding swallowing symptoms.

Furthermore they will undergo flexible laryngoscopy for evaluation of laryngeal mobility.

Study Timeline

• Study Start: 2012-03
• Status Verified: 2012-05
• Study First Submitted: 2012-05-22
• Study First Submitted QC: 2012-05-24
• Last Update Submitted: 2012-05-24
• Study First Posted: 2012-05-30
• Last Update Posted: 2012-05-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• All patients submitted to total thyroidectomy during the study period

Exclusion Criteria

• Previous thyroid/ neck surgery
• Documented voice disorders

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
patients	Swallowing Assesment	patients undergoing total thyroidectomy
patients	Endoscopy of larynx	patients undergoing total thyroidectomy
patients	Voice Handicap Index	patients undergoing total thyroidectomy

Primary Outcome Measures

Name	Time	Method
Subjective voice evaluation	1 week postoperatively	Greek- version of Voice Handicap Index (VHI)
Subjective Voice Evaluation	1 month postoperatively	Greek- version of Voice Handicap Index (VHI)

Secondary Outcome Measures

Name	Time	Method
Swallowing evaluation	1 month postoperatively	questionnaire on swallowing symptoms

Trial Locations

Locations (1)

University Hospital of Larissa; 🇬🇷 Larissa, Greece