Improvement in arthritis following improvement in oral health by cleaning of the teeth
- Conditions
- Health Condition 1: M059- Rheumatoid arthritis with rheumatoid factor, unspecified
- Registration Number
- CTRI/2020/03/023692
- Lead Sponsor
- Government Dental college and Research InstituteBangalore
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 0
1.Subjects in the age group of 30-60 years.
2.Both male and female subjects. (Inclusive)
3.Subjects with Rheumatoid arthritis (diagnosed based on 2010 ACR/EULAR Classification Criteria for RA).
4.Periodontitis (Stage I and stage II periodontitis, Grade A and B.) as per 2017 classification of periodontal disease and conditions)
1.Subjects with Periodontal abscess and Endodontic-Periodontal lesions, Necrotizing Periodontal diseases, or periodontitis as a manifestation of systemic disease.
2.Subjects with tobacco consumption in any form.
3.Subjects with systemic diseases or conditions affecting the periodontal supporting tissues.
4.Subjects with systemic disease and conditions affecting the course of Rheumatoid arthritis.
5.Subjects who had received periodontal therapy in the last six month.
6.Subjects who had received antibiotics 3 months preceding the examination or may require antibiotic therapy during the study period.
7.Subjects with neoplastic conditions or severe systemic infections like HIV, HEPATITIS B etc.
8.Pregnant and lactating women.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary out come: Assessment of serum CRP and ACPA level, <br/ ><br>Timepoint: Primary out come: Assessment of serum CRP and ACPA level at baseline,2 months <br/ ><br>
- Secondary Outcome Measures
Name Time Method DAS 28 score, probing pocket depth and clinical attachment level,plaque score , bleeding on probingTimepoint: At baseline,2 months,4 months and 6 months.