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Clinical Trials/EUCTR2015-003633-10-FI
EUCTR2015-003633-10-FI
Active, not recruiting
Phase 1

Optimizing the antibiotic treatment of uncomplicated acute appendicitis: a prospective randomized multicenter study - APPACII

Turku University Hospital0 sites552 target enrollmentDecember 22, 2015
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Conditionsncomplicated acute appendicitisMedDRA version: 20.1Level: LLTClassification code 10000677Term: Acute appendicitisSystem Organ Class: 100000004862Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Therapeutic techniques [E02]
DrugsMoxifloxacinLevofloxacinMetronidazoleErtapenem

Overview

Phase
Phase 1
Intervention
Not specified
Conditions
ncomplicated acute appendicitis
Sponsor
Turku University Hospital
Enrollment
552
Status
Active, not recruiting
Last Updated
8 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
December 22, 2015
End Date
TBD
Last Updated
8 years ago
Study Type
Interventional clinical trial of medicinal product
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • •1\) Signed informed consent, 2\) Age 18 – 60 years, 3\) CT scan confirmed diagnosis of uncomplicated acute appendicitis.
  • •Are the trial subjects under 18? no
  • •Number of subjects for this age range:
  • •F.1\.2 Adults (18\-64 years) yes
  • •F.1\.2\.1 Number of subjects for this age range 552
  • •F.1\.3 Elderly (\>\=65 years) no
  • •F.1\.3\.1 Number of subjects for this age range

Exclusion Criteria

  • •1\) Age \<18 or \> 60 years, 2\) Pregnancy or lactating, 3\) Allergy to contrast media or iodine, 4\) Renal insufficiency, 5\) Metformine medication, 6\) Severe systemic illness (for example malignancy, medical condition requiring immunosuppressant medications), 7\) Complicated acute appendicitis in a CT scan (appendicolith, perforation, abscess, suspicion of a tumor), 8\) Inability to co\-operate and give informed consent.

Outcomes

Primary Outcomes

Not specified

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