Optimizing the antibiotic treatment of uncomplicated acute appendicitis

Phase 1

• Conditions: ncomplicated acute appendicitis; MedDRA version: 20.1Level: LLTClassification code 10000677Term: Acute appendicitisSystem Organ Class: 100000004862; Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Therapeutic techniques [E02]

• Registration Number: EUCTR2015-003633-10-FI
• Lead Sponsor: Turku University Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2015-12-22
• Last Update Posted: 5 February 2018

Recruitment & Eligibility

• Status: Authorised-recruitment may be ongoing or finished
• Sex: All
• Target Recruitment: 552

Inclusion Criteria

1) Signed informed consent, 2) Age 18 – 60 years, 3) CT scan confirmed diagnosis of uncomplicated acute appendicitis.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 552
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

1) Age <18 or > 60 years, 2) Pregnancy or lactating, 3) Allergy to contrast media or iodine, 4) Renal insufficiency, 5) Metformine medication, 6) Severe systemic illness (for example malignancy, medical condition requiring immunosuppressant medications), 7) Complicated acute appendicitis in a CT scan (appendicolith, perforation, abscess, suspicion of a tumor), 8) Inability to co-operate and give informed consent.

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified