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临床试验/NCT06285175
NCT06285175
已完成
不适用

REINVENT: A Brain and Muscle Computer Interface for People With Severe Stroke

University of Southern California1 个研究点 分布在 1 个国家目标入组 14 人2021年6月1日
适应症Stroke

概览

阶段
不适用
干预措施
未指定
疾病 / 适应症
Stroke
发起方
University of Southern California
入组人数
14
试验地点
1
主要终点
Fugl Meyer Assessment - Upper Extremity
状态
已完成
最后更新
2年前

概览

简要总结

Stroke is a leading cause of adult disability in the United States. High doses of repeated task-specific practice have shown promising results in restoring upper limb function in chronic stroke (>6 months after onset). However, it is currently challenging to provide such doses in standard clinical practice. At-home telerehabilitation services supervised by a clinician are a potential solution to provide higher-dose interventions. However, telerehabilitation systems developed for repeated task-specific practice typically require a minimum level of active movement. Therefore, severely impaired people necessitate alternative therapeutic approaches. Measurement and feedback of electrical muscle activity via electromyography (EMG) have been previously implemented in the presence of minimal or no volitional movement to improve motor performance in people with stroke. Specifically, muscle neurofeedback training to reduce unintended co-contractions of the impaired hand may be a targeted intervention to improve motor control in severely impaired populations. In this study, we examine the effects of a low-cost, portable, and modular EMG biofeedback system (Tele-REINVENT) for supervised and unsupervised upper limb telerehabilitation after stroke during a 6-week home-based training program that reinforces activity of the wrist extensor muscles while avoiding coactivation of flexor muscles via computer games.

注册库
clinicaltrials.gov
开始日期
2021年6月1日
结束日期
2024年2月15日
最后更新
2年前
研究类型
Interventional
研究设计
Single Group
性别
All

研究者

责任方
Principal Investigator
主要研究者

Sook-Lei Liew

Associate Professor

University of Southern California

入排标准

入选标准

  • Moderate to severe upper extremity hemiparesis and residual hand function (e.g., less than 20 degrees of active wrist or finger extension and enough muscle activity to measure with electromyography).

排除标准

  • Taking anti-spasticity medication
  • Significant vision loss (corrected vision is acceptable)
  • Receptive aphasia
  • Hand contractures
  • Secondary neurological disease

结局指标

主要结局

Fugl Meyer Assessment - Upper Extremity

时间窗: Through study completion, an average of 1 month

This assessment measures upper limb impairment after stroke

Corticomuscular coherence

时间窗: Through study completion, an average of 1 month

This assessment measures the connectivity between the brain and muscles of the affected side as a percentage.

Maximum EMG activity

时间窗: Through study completion, an average of 1 month

This assessment measures trace muscle activity in the affected limb during a controlled movement task

研究点 (1)

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