跳至主要内容
临床试验/NCT05584098
NCT05584098已完成不适用

Modified Early Warning Score (MEWS), Quick Sequential Organ Failure Assessment (qSOFA) and Physiological Parameters Combination to Predict the Occurrence of Sepsis in the Emergency Room

St. Martin De Porress Hospital3 个研究点 分布在 1 个国家目标入组 950 人开始时间: 2022年3月20日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
950
试验地点
3
主要终点
Modified Early Warning Score(MEWS) which quickly determine whether a particular patient needs increased medical attention

研究概览

简要总结

In the development of sepsis treatment of recent years, the demand for medical manpower has increased significantly when patients with sepsis appear because of the expansion of medical care demand and shortened response time related to sepsis Due to the shortage of manpower, a more simple and easy-to-operate inspection method is adopted and artificial intelligence technology is used to assist in the evaluation.

The applicability of physiological indicators MEWS, qSOFA and physiological parameters combination as sepsis screening tools in emergency department (ED) and predicting sepsis outcome in the emergency department. When patients with sepsis appear, artificial intelligence technology is used to remind the physicians to respond and administer drugs as soon as possible.

This is a single-center retrospective study of a group of patients admitted to the emergency department. The medical records were reviewed, mainly based on the hospital site records and the existing vital signs of the patients. Attended a hospital emergency room between January 2020 and December 2022. Physiological numerical indicators MEWS and qSOFA were all scored to understand the distribution of sepsis.

详细描述

  1. A single-center retrospective study of a cohort of patients admitted to the emergency department
  2. To see a doctor in the emergency department of the hospital between January 2020 and December 2022, review their medical records, and focus on the hospital's on-site records and the existing patient's vital signs.
  3. The physiological indicators MEWS and qSOFA were scored to understand the distribution of sepsis.
  4. Remind the doctor when a suspected sepsis patient appears under level 5 triage and use artificial intelligence technology to assist
  5. This study will explore the specific improvement practices and effects of improving the response of patients with sepsis when they see a doctor
  6. To analyze and evaluate the economics and benefits of this operation mode, improve the accuracy of emergency inspection of sepsis patients and improve the rationality of hospital manpower deployment
  7. Scheduled progress of the plan: Patients who visited the emergency department of the hospital between January 2020 and December 2022 were included in this study under investigation. This is a retrospective study, and patients are required to undergo necessary examinations according to their own conditions, without any interference from the study

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Screening
盲法
None

盲法说明

Mask all identified labels in all raw data

入排标准

性别
All
接受健康志愿者

入选标准

  • This is a single-center retrospective study of a group of patients admitted to the emergency department.

排除标准

  • Patients with incomplete treatment clinical data, lack of information in medical records, trauma patients

结局指标

主要结局

Modified Early Warning Score(MEWS) which quickly determine whether a particular patient needs increased medical attention

时间窗: From date of randomization until the date of first documented progression assessed up to 36 months

MEWS score = Systolic blood pressure + Heart rate + Urine output + Respiratory rate + Temperature + AVPU. The lowest score is 0 and highest score is 14. The more score will show more severe disease. MEWS score:Description Risk of death or ICU admission \<3: patient in a stable condition, 3-4: Signs of respiratory failure. Consider higher level of care, ≥5: Patient in a critical condition. Higher level of care recommended

qSOFA used in emergency medicine department

时间窗: From date of randomization until the date of first documented progression assessed up to 36 months

The qSOFA score is a simple score consisting of three items: respiratory rate (RR) ≥ 22 breaths per minute, altered mentation (Glasgow Coma Scale \[GCS\] \< 15), and systolic blood pressure (SBP) \< 100 mmHg and lowest score is 1 and highest is 3. The more score will show more severe disease. MEWS score:Description Risk of death or ICU admission \<3: patient in a stable condition, 3-4: Signs of respiratory failure. Consider higher level of care, ≥5: Patient in a critical condition. Higher level of care recommended

qSOFA used in emergency medicine department

时间窗: From date of randomization until the date of first documented progression assessed up to 36 months

The qSOFA score is a simple score consisting of three items: respiratory rate (RR) ≥ 22 breaths per minute, altered mentation (Glasgow Coma Scale \[GCS\] \< 15), and systolic blood pressure (SBP) \< 100 mmHg and lowest score is 1 and highest is 3. The more score will show more severe disease. MEWS score:Description Risk of death or ICU admission \<3: patient in a stable condition, 3-4: Signs of respiratory failure. Consider higher level of care, ≥5: Patient in a critical condition. Higher level of care recommended

Modified Early Warning Score(MEWS) which quickly determine whether a particular patient needs increased medical attention

时间窗: From date of randomization until the date of first documented progression assessed up to 36 months

MEWS score = Systolic blood pressure + Heart rate + Urine output + Respiratory rate + Temperature + AVPU. The lowest score is 0 and highest score is 14. The more score will show more severe disease. MEWS score:Description Risk of death or ICU admission \<3: patient in a stable condition, 3-4: Signs of respiratory failure. Consider higher level of care, ≥5: Patient in a critical condition. Higher level of care recommended

physiological parameters combination

时间窗: From date of randomization until the date of first documented progression assessed up to 36 months

Shock Index (SI) = Heart Rate / Systolic Blood Pressure Age-Adjusted Shock Index (Age SI) = Age x Shock Index Respiratory-Adjusted Shock Index (RASI) = HR/SBP × (RR/10)

次要结局

未报告次要终点

研究者

发起方
St. Martin De Porress Hospital
申办方类型
Other
责任方
Principal Investigator
主要研究者

Chia-hsi Chen

attending physician,emergency medicine department

St. Martin De Porress Hospital

研究点 (3)

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