NCT00956878已完成不适用
Storage and Analysis of Patient Blood-samples for Cancer Pain Research
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 243
- 试验地点
- 1
- 主要终点
- correlation between pain SNPs and equianalgesic opioid requirement
研究概览
简要总结
Cancer pain is common in advanced cancer patients. Opioids are the mainstay of treatment in cancer pain. Responsiveness to and tolerability of opioids is, amongst others, determined by small variations in human DNA. Using blood samples from clinically well-defined cancer pain patients, the investigators are going to analyze single nucleotide polymorphisms (SNPs) in genes that are known to be involved in responsiveness to opioids and sensitivity to pain.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Cancer pain patients
排除标准
- •Patients not able to provide informed consent
结局指标
主要结局
correlation between pain SNPs and equianalgesic opioid requirement
时间窗: timepoint at blood sample
candidate SNP analysis
次要结局
未报告次要终点
研究者
Joost LM Jongen
Dr. J.L.M. Jongen, MD, PhD
Erasmus Medical Center
研究点 (1)
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