The effect of oral Crocus Sativus (Saffron) tablet on cervical ripening in pregnant women with gestational age of 39-41 weeks
- Conditions
- Cervical ripening.Primary inadequate contractions
- Registration Number
- IRCT201212233706N19
- Lead Sponsor
- Research deputy of Tabriz university of medical sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 50
1. Women with 1-3 gravidity and gestational age of 39-41 weeks 2. Not starting uterine contractions 3. Willing to deliver in Bonab hospital 4. Secondary and higher educational level 5. Bishop score of four or less 6. Singleton pregnancy 7. Cephalic presentation 8. Intact amniotic sac 9. Reactive non-stress test 10. Estimated fetal weight of 2500 to 4000 grams by ultrasound or examination.
Exclusion criteria: 1. History of cryotherapy or cautery of the cervix 2. History of cesarean or having any indication for cesarean section in current pregnancy 3. Diagnosed fetal anomalies 4. Cephalo-Pelvic Disproportion 5. Any known placental problem (placenta previa, placental abruption, placental insufficiency) 6. Maternal infection and systemic chronic diseases, including respiratory diseases, cardio - vascular, endocrine and... 7. Using any of the following drugs by the woman (oral hypoglycemic agents and insulin, anticoagulants such as aspirin and Warfarin ,non steroidal -anti-inflammatory drugs such as ibuprofen and naproxen, herbal drugs and antihypertensives, benzodiazepines such as lorazepam and diazepam, barbiturates such as phenobarbital, narcotics, antidepressant, Alcohol) 8. Not access to telephone line
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Bishop score. Timepoint: Befor intervention, at the time of onset of uterin contractions, 10-12 and 20-24 hours after intervention or at the time of doing other treatment interventions. Method of measurement: The Bishop rating system.
- Secondary Outcome Measures
Name Time Method Duration of the first stage of labor. Timepoint: After finishing the first stage of labor. Method of measurement: Patient record.;Interval of onset of uterine active contractions and starting intervention. Timepoint: In the 24 hours after starting intervention. Method of measurement: Patient and clinician report.;Duration of the second stage of labor (in minutes). Timepoint: After finishing the second stage of labor. Method of measurement: Observation and physical exam.;Need to induce labor. Timepoint: Between admission in delivery room and delivery. Method of measurement: According to hospital records.;Delivery type. Timepoint: After delivery. Method of measurement: According to hospital records.;Vaginal delivery in 24 hours after starting intervention. Timepoint: 24 hours after intervention. Method of measurement: According to hospital records.;Amount of hemorrhage. Timepoint: The time of admission in delivery room and 12 hours after delivery. Method of measurement: Hematocrit assessment.