Influence of lactate on the brain and lipid metabolism.
Recruiting
- Conditions
- familial combined hyperlipidemia
- Registration Number
- NL-OMON21752
- Lead Sponsor
- Academic medical center
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
Healthy participants inclusion:
1. Male;
Exclusion Criteria
Medication influencing the brain.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method TG-VLDL synthesis by the liver measured by stable glycerol isotopes every hour. With the rate of disappearance curve synthesis will be calculated.
- Secondary Outcome Measures
Name Time Method MRS changes in brain to define lactate levels in the brain.