Does heat conditioning improve health in peripheral arterial disease?

Not Applicable

Completed

• Conditions: peripheral arterial disease; Cardiovascular - Diseases of the vasculature and circulation including the lymphatic system

• Registration Number: ACTRN12616001049460
• Lead Sponsor: Associate Prof. Jim Cotter

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-08-05
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

1) PAD confirmed by ankle-brachial index in at least one leg of <=0.8 at rest and/or a reduction following exercise;
2) Mild to moderate claudication described, corresponding to Fontaine stage IIa to IIb;
3) > 45 years old;
4) Females must be post-menopausal and not taking hormone replacement therapy;
5) Able to comply with study requirements including repeat visits to the laboratory.

Exclusion Criteria

1) Functioning bypass graft in-situ;
2) Isolated disease in aorta / iliac vessels;
3) Type 1 diabetes;
4) Previous occurence of heat intolerance;
5) Unstable angina or myocardial infarction in the past 12 months;
6) Evidence of clinically significant ischaemic heart disease present in the cardiac stress test, and deemed so by the cardiologist.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
6-minute walking distance, performed on a treadmill.<br>[Baseline, 6 weeks and 12 weeks]