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Techniques to Reduce the Severity and Frequency of Emergent Reactions

Not Applicable
Terminated
Conditions
Analgesia
Interventions
Behavioral: Do we speak to them in a way that convinces them to have the dream
Behavioral: Speaking to them as a regualar person
Registration Number
NCT03832309
Lead Sponsor
CHRISTUS Health
Brief Summary

The objectives of this study are first to determine if the power of suggestion will decrease the frequency and severity of emergence reactions after procedural sedation and analgesia with ketamine in the setting of the emergency department. Second, to determine if people dream about what they were thinking about when they were induced with ketamine.

Detailed Description

The proposed research will be single blinded (patient) randomized controlled trial with a retrospective component to test the hypothesis that the power of suggestion will reduce the frequency and severity of emergence reactions, even in the setting of the emergency department.

The study will be conducted in the emergency department at CHRISTU Spohn Shoreline Hospital. CHRISTUS Spohn Shore hospital is the region's primary acute care center. It houses the Chest Pain, Stroke, and Cancer Centers of CHRISTUS Spohn, and the only level II trauma center in south Texas. It is a major teaching affiliate of Texas A\&M medical school, and serves an inner-city population.

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
38
Inclusion Criteria
  • Be at least 18 years of age
  • Required need for procedural sedation and analgesia
Exclusion Criteria
  • Age< 18
  • Hypertension
  • Raised Intracranial pressure
  • Major psychological disorders
  • Procedures involving laryngel manipulations
  • History of Laryngeal sapsm History of adverse reactions to ketamine

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Control ArmDo we speak to them in a way that convinces them to have the dreamHalf of the participants will receive the sedation medication with the usual conversation while the physician is giving the medication to the patient. The other half of the participants will have a more positive conversation, (which is the study intervention), with the physician while being given the medication. Both group's emergence reactions, if any, will be compared to see if the positive conversation reduced the side effect.
Group 1Do we speak to them in a way that convinces them to have the dreamPacket 1: The Physician will be asked to instruct the patient as empathetically and confidently as possible, that the drug the patient will be given will make them feel no pain, cause them to forget the procedure, and allow them to dream the dream of their choice.
Control ArmSpeaking to them as a regualar personHalf of the participants will receive the sedation medication with the usual conversation while the physician is giving the medication to the patient. The other half of the participants will have a more positive conversation, (which is the study intervention), with the physician while being given the medication. Both group's emergence reactions, if any, will be compared to see if the positive conversation reduced the side effect.
Group 1Speaking to them as a regualar personPacket 1: The Physician will be asked to instruct the patient as empathetically and confidently as possible, that the drug the patient will be given will make them feel no pain, cause them to forget the procedure, and allow them to dream the dream of their choice.
Primary Outcome Measures
NameTimeMethod
STAI-624 months

To ensure two groups are similar to each other -demographic data, the pre and post opt sedation VAS scores, and the STAI-6 information.

T-Test24 months

Data gathered from post sedation questionnaire, specifically question 5, will be analyzed by comparing the two means of group one and group two using a student's T test,

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

CHRISTUS Health

🇺🇸

Corpus Christi, Texas, United States

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