The efficacy of curcuminoid in patients with overlapping gastroesophageal reflux disease and functional dyspepsia: A randomized controlled trial.

Government Pharmaceutical Organization (GPO)0 个研究点目标入组 86 人开始时间: 2018年5月30日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•Diagnosis criteria for acid reflux disease are:
•1. Age 18 - 70 years
•2. Patients with burning sensation or tightness in the chest. And / or have food Stomach back up in the esophagus and / or sour or bitter. These symptoms interfere with the quality of life.
•Functional dyspepsia ROME IV criteria30 means patients with at least one of the following symptoms:
•- Bothersome postpradial fullness
•- Early satiety
•- Epigastric pain
•- Epigastriac burning pain
•Symptoms Continued at least 3 months and started onset for at least 6 months.
•3. Upper gastrointestinal endoscopy for 6 months prior to study.

•1. Surgery in the abdomen except appendicitis, Maternity leave
•2. Cancer of the gastrointestinal tract and liver
•3. chronic inflammatory bowel disease inflammatory bowel disease
•4. Cirrhosis, Chronic kidney disease
•5. Depression
•6. Upper gastrointestinal endoscopy results in 6 months before admission. The following abnormalities were observed: esophagus, gastric ulcer and duodenal ulcer.
•7. Helicobacter pylori infection
•8. Patients who take the drug with gastrointestinal effects and can not off the drug during research.
•9. There are neurological diseases that can not be evaluated for pain. Uncontrolled psychiatric disorders and may want to adjust the drugs during study.
•10. Have allergic curcumin.
•11. Eat foods that component curcumin, regularly at least 3 days a week during the 1 month prior to study
•12. Patients who can not sign the consent form for study participation.

发起方

Government Pharmaceutical Organization (GPO)