Effect of Real-time Continuous Glucose Monitoring on Glucose Control and Outcomes of Critically Ill Patients
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 144
- Locations
- 1
- Primary Endpoint
- Glycemic Control Measures including: Percentage of target blood glucose levels (defined as between 8mmol/L and 10mmol/L); Time of hyperglycemia (defined as >10mmol/L); Hypoglycemia rate (defined as < 2.2mmol/L); Glucose lability index
Study Overview
Brief Summary
The purpose of the study is to evaluate the effect of real-time continuous glucose monitoring system on glucose control and outcomes of critically ill patients.
Detailed Description
Real-time continuous glucose monitoring system has shown great accuracy and feasibility in critically ill patients. However, its impact on glucose control and outcomes has nearly unknown. Thus, Investigators designed this study to evaluate the effect of real-time continuous glucose monitoring system on glucose control and outcomes of critically ill patients.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Double (Participant, Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •More than 18 years old male or female;
- •Expected ICU stays longer than 72 hours;
- •Glucose level more than 8 mmol/L when enrolls in the ICU;
- •Patients or their legal surrogates have signed the informed consent.
Exclusion Criteria
- •Pregnant or lactating women;
- •ICU stays less than 72 hours;
- •Usage of real-time continuous glucose monitoring system is considered as a contraindication.
Outcomes
Primary Outcomes
Glycemic Control Measures including: Percentage of target blood glucose levels (defined as between 8mmol/L and 10mmol/L); Time of hyperglycemia (defined as >10mmol/L); Hypoglycemia rate (defined as < 2.2mmol/L); Glucose lability index
Time Frame: Glycemic control measures will be assessed up to five days.
Secondary Outcomes
- Prognosis Measures including: Duration of mechanical ventilation；Time of ICU stay; Time of hospital stay; 28 days - mortality rate(All the participants will be followed for the duration of hospital stay or 28 days.)
- Cost(Cost associated with glucose monitoring)
Investigators
Kang Yan
Director of Intensive Care Unit
West China Hospital