A single-arm exploratory study examining the feasibility of imaging glioblastoma pH using CEST-MRI

niversity of Oxford0 sites19 target enrollmentAugust 7, 2017

Overview

No summary available.

Registry

who.int

Start Date

August 7, 2017

End Date

June 15, 2021

Last Updated

4 years ago

Study Type

Interventional

Sex

All

Sponsor

•1\. Participant is willing, capable of cooperating with the protocol and able to give informed consent for participation in the study
•2\. Male or female, aged 18 years or above
•3\. Diagnosed with glioblastoma and scheduled for neurosurgical resection or debulking

•Current exclusion criteria as of 16/02/2018:
•1\. Intolerant of MRI brain (for example: claustrophobia)
•2\. MRI brain contraindicated (for example: implanted electric and electronic devices, heart pacemakers, insulin pumps, implanted hearing aids, neurostimulators, intracranial metal clips, metallic bodies in the eye)
•3\. Neoadjuvant chemotherapy/radiotherapy treatment for glioblastoma which would interfere with the interpretation of trial results
•4\. Pregnancy
•5\. Other psychological, social or medical condition that the investigator considers would make the patient a poor trial candidate or could interfere with protocol compliance or the interpretation of trial results
•Previous exclusion criteria:
•1\. Intolerant of MRI brain (for example: claustrophobia)
•2\. MRI brain contraindicated (for example: implanted electric and electronic devices, heart pacemakers, insulin pumps, implanted hearing aids, neurostimulators, intracranial metal clips, metallic bodies in the eye)
•3\. Prior treatment for glioblastoma