Value of the Analgesia Nociception Index (ANI) to intraoperatively predict changes in blood pressure and heart rate
Not Applicable
Completed
- Conditions
- Heart rate and systolic blood pressure in anaesthetized patientsNociception (by means of the analgesia nociception index)Anaesthesiology - AnaestheticsNeurological - Studies of the normal brain and nervous system
- Registration Number
- ACTRN12613000212752
- Lead Sponsor
- Thomas Ledowski
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Patients scheduled for non-emergency surgery planned to be anaesthetized using sevoflurane and fentanyl.
Exclusion Criteria
Patients on medication with beta-receptorblockers, clonidine, ketamine, continuous infusion of vasoactive substances, neostigmine, glycopyrrolate or atropine. Patients with incapacity to consent, < 18 years or patients who not wish to participate. Patients with an allergy to sticky ecg electrodes as well as patients with a pacemaker. Patients whose surgery will include use of a tourniquet will also be excluded.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Predictive value of ANI for changes of systolic blood pressure or heart rate within a 5-minute interval (5 minutes from ANI change) in patients undergoing non-emergency surgery[intraoperatively. Multiple events possible. ANI changes > 20% from baseline are named ANI event. A period of 5 minutes after such event is observed for changes in HR or blood pressure (> 10%) ]
- Secondary Outcome Measures
Name Time Method Changes in ANI after (within 5 minutes) changes in heart rate or blood pressure (changes of HR and BP defined as > 15% from baseline)[intraoperatively. Observation of ANI for 5 minutes after changes in heart rate of blood pressure (> + 15% from baseline)]