Correlation between clinical features and laboratory parameters in adult patients having atopic dermatitis
- Conditions
- Health Condition 1: L209- Atopic dermatitis, unspecified
- Registration Number
- CTRI/2023/06/053581
- Lead Sponsor
- Society for eczema Studies
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
(a)Age at presentation equal to or more than 18 years
(b)Active atopic dermatitis diagnosis of which shall be made on 2 grounds
1. Fulfilment of Hanifin and Rajkaâ??s original criteria
2. Expert opinion where 3 independent eczema experts decide unanimously on the diagnosis of adult AD
(a)Pregnancy and lactation
(b)Any immunocompromised state
(c)Patients with a history or physical exam suggestive of other causes of eosinophilia common in our settings-helminthic infection, DRESS(drug reaction with eosinophilia and systemic symptoms), bullous pemphigoid, chronic bullous disease of childhood , fungal infections, chronic pancreatitis, primary gastrointestinal eosinophilic disorders including inflammatory bowel disease, eosinophilic esophagitis, coeliac diseases, rheumatological disease-systemic lupus erythematosus, eosinophilic fasciitis (Shulman disease) , vasculitis - polyarteritis nodosa and eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome), rheumatoid arthritis and acute and chronic eosinophilic pneumonia (that includes Loeffler syndrome, sarcoidosis, allergic bronchopulmonary aspergillosis)
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Classification of clinical characteristics of adult patients having AD into the following four subgroups as mentioned below <br/ ><br>1.High IgE & Eosinophilia <br/ ><br>2.Normal IgE & Eosinophilia <br/ ><br>3.High IgE and Normal Eosinophils <br/ ><br>4.Normal IgE and Normal Eosinophils <br/ ><br>Timepoint: 1.5 years <br/ ><br>
- Secondary Outcome Measures
Name Time Method IL-4 levels in the different subgroupsTimepoint: 1.5 years