Palmoplantar Pustulosis and Generalized Pustular Psoriasis: A National Population-based Analysis of Prevalence

• Conditions: Generalized Pustular Psoriasis; Palmoplantar Pustulosis
• Interventions: Other: prevalence/incidence

• Registration Number: NCT04566471
• Lead Sponsor: Peking University Third Hospital

Brief Summary

This study plans to calculate the prevalence and incidence of palmoplantar pustulosis and generalized pustular psoriasis based on the national medical insurance data and analyze the composition characteristics and some clinical features of patients, through taking into account of the research status of palmoplantar pustulosis and generalized pustular psoriasis and the characteristics of medical insurance data.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-01-01
• Primary Completion: 2016-12-01
• Status Verified: 2020-06
• Study First Submitted: 2020-09-22
• Study First Submitted QC: 2020-09-22
• Last Update Submitted: 2020-09-22
• Study First Posted: 2020-09-28
• Last Update Posted: 2020-09-28
• Study Completion: 2021-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• The insured population of the national urban employee basic medical insurance and the urban resident basic medical insurance from January 1, 2012, to December 31, 2016 (60 months) (the denominator)
• The patients have been diagnosed with palmoplantar pustulosis or generalized pustular psoriasis (including disease name, English abbreviation and ICD code)
• Both outpatient and inpatient patients are included

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Exclusion Criteria

• The individuals whose information is only contained in the reimbursement settlement database but not in the insurance coverage database will be considered as invalid reimbursement individuals and be excluded from the study (the denominator)
• The patients have been diagnosed with non-PPP and -GPP diseases, such as pustular psoriasis in palm and toe, pustular arthritis osteitis and SAPHO syndrome

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
PPP and GPP	prevalence/incidence	Palmoplantar pustulosis (PPP) and Generalized pustular psoriasis (GPP) are rare chronic inflammatory skin diseases, characterized by repeated episodes of sterile pustules in several months or years, associated with erythrokeratodermia generally. Both two diseases are easy to cause skin rupture, leading to bleeding and pain.

Primary Outcome Measures

Name	Time	Method
prevalence of Palmoplantar pustulosis	From 2012 to 2016 in the Urban Employee Basic Medical Insurance (UEBMI) data of China	Epidemiological characteristics of diseases: Mainly referring to indicators that could reflect the frequency related to the disease
prevalence of Generalized pustular psoriasis	From 2012 to 2016 in the Urban Employee Basic Medical Insurance (UEBMI) data of China	Epidemiological characteristics of diseases: Mainly referring to indicators that could reflect the frequency related to the disease

Secondary Outcome Measures

Name	Time	Method
incidence of Palmoplantar pustulosis	From 2012 to 2016 in the Urban Employee Basic Medical Insurance (UEBMI) data of China	Epidemiological characteristics of diseases: Mainly referring to indicators that could reflect the frequency related to the disease
incidence of Generalized pustular psoriasis	From 2012 to 2016 in the Urban Employee Basic Medical Insurance (UEBMI) data of China	Epidemiological characteristics of diseases: Mainly referring to indicators that could reflect the frequency related to the disease
Economic burden of Palmoplantar pustulosis	From 2012 to 2016 in the Urban Employee Basic Medical Insurance (UEBMI) data of China	Mainly referring to the consumption of medical resources, including medical expenses of patients.
Economic burden of Generalized pustular psoriasis	From 2012 to 2016 in the Urban Employee Basic Medical Insurance (UEBMI) data of China	Mainly referring to the consumption of medical resources, including medical expenses of patients.