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Clinical Trials/NCT01725711
NCT01725711
Active, not recruiting
Not Applicable

Osseointegrated Prostheses for the Rehabilitation of Amputees.

Integrum1 site in 1 country51 target enrollmentMay 1999

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Transfemoral Amputation
Sponsor
Integrum
Enrollment
51
Locations
1
Primary Endpoint
Q-TFA Prosthetic Use Score
Status
Active, not recruiting
Last Updated
6 years ago

Overview

Brief Summary

Patients with transfemoral amputations (TFA) frequently experience problems related to the use of socket-suspended prostheses 1-3. These problems increase with short or deformed stumps 4. The potential for improvement is substantial. Based on the very good long-term results with osseointegrated titanium implants for edentulous patients 5, osseointegrated hearing aids 6, cranio-facial prostheses 7 and prostheses for thumb-amputated patients 8, the clinical development of osseointegrated prostheses for TFA started in 1990, in Gothenburg, Sweden. The concept has gradually been modified and improved. In 1999, a prospective clinical trial began.

The hypothesis is that the treatment will improve quality of life.

Registry
clinicaltrials.gov
Start Date
May 1999
End Date
May 2027
Last Updated
6 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Integrum
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Transfemoral amputation

Exclusion Criteria

  • Transfemoral amputation due to vascular disease

Outcomes

Primary Outcomes

Q-TFA Prosthetic Use Score

Time Frame: 0,1,2,3,5,7,10,15,20 years

The primary efficacy variable is the change in Q-TFA Prosthetic Use Score as compared baseline.

Study Sites (1)

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