A study to investigate how common a diagnosis of axial spondyloarthritis (axSpA) is in patients with known inflammatory bowel disease (IBD) such as Crohn’s Disease and Ulcerative Colitis, and the development of a tool to direct referral of patients with suspected axSpA in IBD patients to a rheumatology specialist.
- Conditions
- Axial Spondyloarthritis / Ankylosing SpondylitisMusculoskeletal Diseases
- Registration Number
- ISRCTN30265575
- Brief Summary
2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35993905/ (added 30/08/2022)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 470
Inclusion criteria for Phase 1 (Screening):
1. Gastroenterologist verified diagnosis of inflammatory bowel disease (Crohn’s disease or Ulcerative colitis, with either endoscopic, radiological or histological evidence of disease based on established criteria)
2. Age = 18 and = 80 years old
3. Patient willing and able to participate in the study
4. Including known/previous diagnosis of AS or axSpA
Inclusion criteria for Phase 2 (Clinical assessment):
1. Chronic back pain (= 3 months)
2. Onset of back pain before 45 years old
3. Including known/previous diagnosis of AS or axSpA (if unable to verify diagnosis retrospectively)
1. Any type of biologic therapy for (previous or current) treatment of IBD
2. Unable to tolerate MRI scanning (e.g. current history of claustrophobia) or contra-indication to MRI scanning
(including but not limited to e.g. pacemaker, pregnancy, metallic or conducting foreign body, etc.)
3. Age <18 or >80 years
4. Patients lacking in capacity and/or unable to give informed consent
5. Patients unable to understand English to sufficient degree to be able to complete a questionnaire
6. Illiteracy
7. Prisoners
8. Patient unwilling to take part in the study
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method