Comparison of the effects of flaxseed and sesame powder on the antioxidant activity and blood profile of patients with mild to moderate hypertensio
- Conditions
- Hypertension.Essential (primary) hypertension
- Registration Number
- IRCT2016050727729N2
- Lead Sponsor
- Vice Chancellor for Research and Technology of Shahid Sadoughi University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 90
age between 30 to 65 years; stage I hypertension (Systolic Blood Pressure (SBP) 140-159 mmHg, Diastolic Blood Pressure (DBP) 90-99 mmHg); using a particular anti-hypertensive therapy for at least 3 months; cholesterol less than 240 mg/dl.
pregnant women or women planning to get pregnant; being allergic to sesame or flaxseed; suffering from intestinal diseases such as Crohn's disease, colitis, peptic ulcer, irritable bowel syndrome (IBS), and other severe systemic diseases such as systemic lupus erythematosus (SLE), cancer, or stage IV respiratory diseases; history of myocardial infarction; coronary bypass surgery during last 6 months; stage II hypertension; diabetes; routinely using nonsteroidal anti-inflammatory drugs (NSAID's); change of anti-hypertensive drugs during the study; using drugs for hyperlipidemia
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Free radical scavenging capacity. Timepoint: prior to study, Seventh week, and at the end of study. Method of measurement: this is showed in % and is obtained by measuring DPPH (1,1-diphenyl-2-picryl hydrazyl radical). This measurement is done by Elisa.;Malondialdehyde (MDA). Timepoint: prior to study, Seventh week, and at the end of study. Method of measurement: micromol/L; it is measured by Elisa.;Cholesterol. Timepoint: prior to study, Seventh week, and at the end of study. Method of measurement: mg/dL.;Triglyceride. Timepoint: prior to study, Seventh week, and at the end of study. Method of measurement: mg/dL.;Low density lipoprotein (LDL). Timepoint: prior to study, Seventh week, and at the end of study. Method of measurement: mg/dL.;High density lipoprotein (HDL). Timepoint: prior to study, Seventh week, and at the end of study. Method of measurement: mg/dL.
- Secondary Outcome Measures
Name Time Method