Study of the Occupational Risk of Radiation-induced Cataracts Among Cardiologists
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 250
- 试验地点
- 1
- 主要终点
- Lens opacities
研究概览
简要总结
The purpose of this study is to test the existence of an increased risk of cataracts among interventional cardiologists as compared to cardiologists not exposed to X-rays.
详细描述
This cross-sectional study includes cardiologists aged > 40 years: a group of interventional cardiologists (coronary interventionists and electrophysiologists) and a group of unexposed workers (including cardiologists). Individual information, including risk factors of cataracts (age, diabetes, myopia, etc. ...), are collected during a telephone interview. For the exposed group, a specific section of the questionnaire is focused on the occupational history, the description of the procedures (type, frequency, radiation protection tool) and will be used for the classification into "comparable exposure level" groups according to estimates of cumulative dose. For all participants, eye examinations are performed to specifically detect cataracts even in the early stages (lens opacities, LOCS III according to the international standard classification).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 40 Years 至 75 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •aged at least 40 yrs old
- •for interventional cardiologists: cumulated number of procedures > 2000
排除标准
- •previous history of medical radiation exposure for radiotherapy or brain scans
- •for non-interventional cardiologists: occupational history of interventional cardiologist
结局指标
主要结局
Lens opacities
时间窗: up to 1.5 year
次要结局
- Visual acuity(up to 1.5 year)
- Major eye disorders (glaucoma, etc…)(up to 1.5 year)
研究者
Sophie JACOB
PhD
Institut de Radioprotection et de Surete Nucleaire
