跳至主要内容
临床试验/NCT01061463
NCT01061463已完成不适用

Study of the Occupational Risk of Radiation-induced Cataracts Among Cardiologists

Sophie JACOB1 个研究点 分布在 1 个国家目标入组 250 人开始时间: 2009年10月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
250
试验地点
1
主要终点
Lens opacities

研究概览

简要总结

The purpose of this study is to test the existence of an increased risk of cataracts among interventional cardiologists as compared to cardiologists not exposed to X-rays.

详细描述

This cross-sectional study includes cardiologists aged > 40 years: a group of interventional cardiologists (coronary interventionists and electrophysiologists) and a group of unexposed workers (including cardiologists). Individual information, including risk factors of cataracts (age, diabetes, myopia, etc. ...), are collected during a telephone interview. For the exposed group, a specific section of the questionnaire is focused on the occupational history, the description of the procedures (type, frequency, radiation protection tool) and will be used for the classification into "comparable exposure level" groups according to estimates of cumulative dose. For all participants, eye examinations are performed to specifically detect cataracts even in the early stages (lens opacities, LOCS III according to the international standard classification).

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Cross Sectional

入排标准

年龄范围
40 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • aged at least 40 yrs old
  • for interventional cardiologists: cumulated number of procedures > 2000

排除标准

  • previous history of medical radiation exposure for radiotherapy or brain scans
  • for non-interventional cardiologists: occupational history of interventional cardiologist

结局指标

主要结局

Lens opacities

时间窗: up to 1.5 year

次要结局

  • Visual acuity(up to 1.5 year)
  • Major eye disorders (glaucoma, etc…)(up to 1.5 year)

研究者

发起方
Sophie JACOB
申办方类型
Other Gov
责任方
Sponsor Investigator
主要研究者

Sophie JACOB

PhD

Institut de Radioprotection et de Surete Nucleaire

研究点 (1)

Loading locations...

相似试验