Predicting Long-term Outcomes After Cardiac Arrest by Using Serum NGAL: A Prospective, Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 73
- 试验地点
- 1
- 主要终点
- Long term neurologic outcome
研究概览
简要总结
This study was performed to determine the prognosis of patients after cardiac arrest using serum markers called NGAL. The initial NGAL values of patients with post-cardiac arrest syndrome are checked by blood tests, and the long-term neurological prognosis and survival rate are collected after 6 months.
详细描述
Serum NGAL is currently being used as a test to determine the likelihood of developing renal failure. However, in a previous study, serum NGAL correlated with neurological prognosis in post cardiac arrest syndrome patients. This prospective study attempts to see the role of serum NGAL as a prognostic factor by including a sufficient number of patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients who underwent targeted temperature management after out-of-hospital cardiac arrest.
排除标准
- •Patients who did not survived 3 days after cardiac arrest.
- •Pre-existing end-stage renal disease or dependence on renal replacement therapy
结局指标
主要结局
Long term neurologic outcome
时间窗: 6 months
Patients' CPC score after 6 months (good outcome : CPC score 1, 2 / poor outcome : CPC score 3, 4, 5)
次要结局
- Proportion of participants with Overall Survival at 6 months(6 months)
研究者
Joo Suk Oh, MD. PhD.
Professor
Uijeongbu St. Mary Hospital