Predicting Long-term Outcomes After Cardiac Arrest by Using Serum NGAL: A Prospective, Observational Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Out-of-Hospital Cardiac Arrest
- Sponsor
- Uijeongbu St. Mary Hospital
- Enrollment
- 73
- Locations
- 1
- Primary Endpoint
- Long term neurologic outcome
- Status
- Terminated
- Last Updated
- last year
Overview
Brief Summary
This study was performed to determine the prognosis of patients after cardiac arrest using serum markers called NGAL. The initial NGAL values of patients with post-cardiac arrest syndrome are checked by blood tests, and the long-term neurological prognosis and survival rate are collected after 6 months.
Detailed Description
Serum NGAL is currently being used as a test to determine the likelihood of developing renal failure. However, in a previous study, serum NGAL correlated with neurological prognosis in post cardiac arrest syndrome patients. This prospective study attempts to see the role of serum NGAL as a prognostic factor by including a sufficient number of patients.
Investigators
Joo Suk Oh, MD. PhD.
Professor
Uijeongbu St. Mary Hospital
Eligibility Criteria
Inclusion Criteria
- •Adult patients who underwent targeted temperature management after out-of-hospital cardiac arrest.
Exclusion Criteria
- •Patients who did not survived 3 days after cardiac arrest.
- •Pre-existing end-stage renal disease or dependence on renal replacement therapy
Outcomes
Primary Outcomes
Long term neurologic outcome
Time Frame: 6 months
Patients' CPC score after 6 months (good outcome : CPC score 1, 2 / poor outcome : CPC score 3, 4, 5)
Secondary Outcomes
- Proportion of participants with Overall Survival at 6 months(6 months)