Influence of Selected Aerobic Exercises in Patients with Multiple Sclerosis

Not Applicable

• Conditions: Musculoskeletal Diseases; Nervous System Diseases

• Registration Number: PACTR202005730797920
• Lead Sponsor: soher mohamed monuir hamza

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-03-20
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Other
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Inclusion Criteria:
1.Relapsing remitting MS recently diagnosed
2.Age range from 20-40 (P fleger CCH F. E.-H., 2010)
3. EDSS (Expanded Disability Status Scale) score less than 5
4. Vitamin D insufficiency less than 20- 30 ng/mL.

Exclusion Criteria

1-Use of vitamin D supplements in the past 3 months.
2-Additional illness that would restrict their function, or suffered from a relapse within the last 4 months, as defined by Polman (Polman et al., 2011).
3-Relapse of disease and corticosteroids use in past month
4-Active inflammation at the start of the study (flu, cystitis etc.)
5-Renal disease
6-Elevated levels of calcium or parathyroid hormone
7-Switching of imunomodulatory drug in past 3 months
8-Hypersensitivity to vitamin D preparations
9-Cognitive impairment interfering with the subject’s ability to provide informed consent.
10-History of hyperparathyroidism, liver disease, tuberculosis, sarcoidosis and kidney stones (Lassmann, h 1999).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
serum vitamin D level

Secondary Outcome Measures

Name	Time	Method
timed 25 walk test for lower limb functional improvement