Skip to main content
Clinical Trials/NCT06163586
NCT06163586
Completed
Not Applicable

Effects of Neonatal Therapeutic Touch and Massage in Very Preterm and Extremely Preterm Neonates: A Randomized Controlled Trial

University of Maryland, Baltimore1 site in 1 country32 target enrollmentNovember 1, 2023

Overview

Phase
Not Applicable
Intervention
Neonatal Touch and Massage Therapy
Conditions
Neonatal Prematurity
Sponsor
University of Maryland, Baltimore
Enrollment
32
Locations
1
Primary Endpoint
Length of stay
Status
Completed
Last Updated
2 months ago

Overview

Brief Summary

The goal of this clinical trial is to learn about the effects of Neonatal Touch and Massage Therapy on premature babies.

The main questions it aims to answer are:

  • Do babies who receive Neonatal Touch and Massage Therapy get discharged sooner from the NICU
  • Does Neonatal Touch and Massage Therapy have a beneficial effect on weight gain, pain and stress responses, and neurodevelopmental outcomes.

Participants assigned to the treatment group will receive Neonatal Touch and Massage Therapy while admitted to the NICU. Researchers will compare their outcomes to a control group, receiving standard NICU care, to see if there are any differences in the length of hospital stay, weight gain, pain scores, neurodevelopmental outcomes, and incidence of other common conditions associated with prematurity.

Detailed Description

The purpose of this study is to determine the effects of Neonatal Touch and Massage Therapy on premature infants in the NICU. Babies enrolled in this study will be randomly assigned to receive Neonatal Touch and Massage or standard NICU care. Babies in the therapy group will be given Neonatal Touch or Massage therapy by certified providers 3 days per week for 5 to 15 minutes. Therapy will be done for a minimum of 4 weeks. The investigators will assess pain and stress responses before and after treatment. The investigators will also review participant's medical records to collect information about weight gain, length of hospitalization, and general health status. After a participant is discharged home, information will be collected about participant's developmental assessments at regularly scheduled NICU follow-up clinic appointments. There are no significant risks with this therapy. Potential benefits of therapy include increased weight gain, shorter hospitalization, decreased pain and stress, and improved developmental outcomes. Information gained from this study could also help future babies.

Registry
clinicaltrials.gov
Start Date
November 1, 2023
End Date
December 30, 2025
Last Updated
2 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Johana Diaz

Assistant professor of pediatrics, Division of neonatology, University of Maryland

University of Maryland, Baltimore

Eligibility Criteria

Inclusion Criteria

  • Infants born or admitted to University of Maryland NICU in the first 14 days of life
  • Gestational age greater than 23 6/7 weeks and less than 32 weeks at birth
  • Deemed medically stable by the medical care team

Exclusion Criteria

  • Life limiting conditions, including genetic syndromes
  • Cyanotic heart disease
  • Requiring major surgery or critically ill at time of intervention
  • Osteopenia of prematurity with an existing fracture

Arms & Interventions

Intervention

This group will receive structured neonatal touch or massage therapy from a certified NICU provider. Therapy will given 3 days a week for 5 to 15 minutes for a minimum of 4 weeks. We will also be collecting data to assess pain and stress responses during the period immediately before, during, and shortly after the therapy. This includes assessment of crying/irritability, behavior state, facial expression, extremities tone, and vital signs (heart rate, breathing rate, and oxygen levels).

Intervention: Neonatal Touch and Massage Therapy

Control

This group will receive standard NICU care, no different than if they were not enrolled in the study.

Outcomes

Primary Outcomes

Length of stay

Time Frame: Day of birth to discharge home, up to 6 months

Total length of hospitalization, from NICU admission to discharge home in days

Secondary Outcomes

  • Linear growth(Through study intervention, an average of 4 weeks)
  • Weight gain(Through study intervention, an average of 4 weeks)
  • Head growth(Through study intervention, an average of 4 weeks)
  • Neurodevelopmental Outcomes(Within in 1 week of NICU discharge or transfer until up to 3 years of age)
  • Pain scores(1 hour before intervention and up to 3 hours post-intervention)

Study Sites (1)

Loading locations...

Similar Trials