Efficacy of Tuina in patients with knee osteoarthritis
- Conditions
- Knee osteoarthritis
- Registration Number
- ITMCTR2100005298
- Lead Sponsor
- Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
1.meet the diagnostic criteria for KOA set by the Guidelines for the diagnosis and treatment of osteoarthritis in 2018, including retropatellar, medial or lateral KOA, etc., with no traumatic aetiology;
2.are aged between 40 and 70 years, and right-handed;
3.have not taken any pain-killing medicine within 1 month;
4.have not received any Tuina treatment within 1 month;
5.have had at least 3 months of knee-pain duration;
6.have an average score of knee pain on VAS >3 (range from 0 to 10) in the past 2 weeks;
7.have I–II degree knee-joint radiological change on the Kellgren-Lawrence scale;
8.have signed an informed consent.
1.are alcohol or drug abusers or are taking other medications;
2.are pregnant or lactating women;
3.are suffering from psychiatric, neurological, gastrointestinal, cardiovascular, infectious, immunological, respiratory or renal illnesses;
4.are suffering from any other chronic pain condition or have a history of head trauma with loss of consciousness;
5.are diagnosed as rheumatoid arthritis or other leg-related pain disorders.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC);
- Secondary Outcome Measures
Name Time Method Patient Global Impression of Severity (PGI-S);36-item Short Form Health Survey (SF-36);The Self-rating Anxiety Scale (SAS);NIH PROMIS Pain Interference Questionnaire (NIH PROMIS);The Visual Analog Scale (VAS);Self-rating Depression Scale (SDS);