The feasibility and efficacy of neoadjuvant FOLFOXIRI followed by laparoscopic surgery for locally advaned rectal cancer: A phase II study
- Conditions
- colorectal cancer
- Registration Number
- JPRN-UMIN000026575
- Lead Sponsor
- Osaka Medical College Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 58
Not provided
1)Requires continuous treatment with systtematic steroids 2)History of other malignancy with a disease-free interval<1years(other than curatively treated cutaneous basal cell carcinoma,curatively treated carcinoma in situ of the cervix,and gastroenterological cancer confirmed to be cured by endoscopic mucosal resection) 3)Active infections Pr evious palliative radiation therapy for bone metastasis or brain metastasis within 2 weeks 4)HBs antigen positive 5)Uncontrolled diarrhea,unstable angia,Uncontrolled diabetes mellitus 6)Serious complications 7)grade1 of neuropathy 8)Pregnant or lactating females,and males and fenales unwilling to use contraception 9)Psychiatric disability that would preclude study compliance 10)Otherwise determined by the investigator to be unsuitable for participation in the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method