AI-Powered Research

Quick Inventory of Depressive Symptomatology score > 6
First episode of depression before age 25
Currently engaged in, or about to start psychosocial treatment in one of the BMRI clinics.

Exclusion Criteria

a) Evidence of other sleep, neurological or primary medical conditions that could explain the current depression and/or contribute to sleep-wake dysfunction;
b) Other primary psychiatric disorders aside from anxiety disorders;
c) Significant alcohol or other substance dependence;
d) Use of medications that affect sleep, circadian rhythms, or alertness within the past month (participants stabilized on an antidepressant medication, stimulants, lithium or melatoninergic agents will not be excluded from the study)
e) Use of medications that may interact with light to produce a photoallergic reaction.
f) Eye or skin condition which may interact with bright light exposure;
g) Regular shift-work within 60-days prior to entry into the study;
h) Recent transmeridian travel.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in severity of depression as measured by the Quick Inventory of Depressive Symptomatology (QIDSA17-SR) <br><br>[between baseline and post (4 weeks) intervention ]

Secondary Outcome Measures

Name	Time	Method
Change in depression as measured by the Quick Inventory of Depressive Symptomatology (QIDSA17-SR) [score between baseline and follow up (8 weeks) ];Associations between changes in sleep wake profile (mean sleep onset time, offset time efficiency and acrophase), as measured by actigraphy, and change in depression severity as measured by the Quick Inventory of Depressive Symptomatology (QIDSA17-SR) [between baseline and post (4 weeks) intervention];Associations between the initial sleep wake profile (mean sleep onset time, offset time efficiency and acrophase), as measured by actigraphy, and change in depression severity as measured by the Quick Inventory of Depressive Symptomatology (QIDSA17-SR) [baseline and post (4 weeks) intervention];Change in Leeds Sleep Evaluation Questionnaire score[between baseline and post (4 weeks) intervention];Change in Fatigue Severity Scale score<br>[between baseline and post (4 weeks) intervention ]