MedPath

Music for Sleep After Stroke

Not Applicable
Recruiting
Conditions
Cardiovascular Diseases
Stroke
Brain Diseases
Vascular Diseases
Sleep Disorder
Insomnia
Sleep Disturbance
Interventions
Behavioral: Mindful music-listening with sleep hygiene
Registration Number
NCT05867290
Lead Sponsor
NHS Greater Glasgow and Clyde
Brief Summary

Sleep difficulties are common following stroke yet effective evidence-based interventions for improving sleep in this population are lacking. A small number of studies have investigated the use of music listening as a way to improve sleep in adults with insomnia.

This study aims to examine whether a mindful music-listening intervention can reduce subjective and objective insomnia symptoms and improve mood and fatigue post-stroke.

Six adults with a clinical diagnosis of stroke presenting with an insomnia disorder will be recruited from stroke services within NHS Greater Glasgow and Clyde. A multiple baseline single case experimental design will be employed. Participants will be randomly allocated to a baseline phase of 7, 11 or 15 days, followed by a five-week mindful music-listening intervention incorporating sleep hygiene. Changes in subjective and objective sleep will be measured using questionnaires and actigraphy, respectively. Mood and fatigue will also be measured. The data will be analysed using visual inspection, Tau-U and multi-level modelling.

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
6
Inclusion Criteria
  • aged 18+ (no upper age limit);
  • clinically and/or radiologically confirmed diagnosis of stroke
  • score of ≤16 on the Sleep Condition Indicator (SCI; (Espie et al, 2018))
  • at least 3-months post-stroke
Exclusion Criteria
  • Transient Ischemic Attack
  • subarachnoid hemorrhage
  • sleep medication commenced within the last 2 weeks (stable medication accepted)
  • significant receptive aphasia or major psychiatric/substance abuse problem preventing engagement in the intervention
  • deafness or severe hearing impairment preventing engagement in the intervention (use of hearing aids does not lead to exclusion where these support sufficient level of hearing for engagement)
  • unable to give informed consent.
  • participation in another intervention study with risk of contamination of study outcomes (determined on a case-by-case basis)

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Intervention PhaseMindful music-listening with sleep hygiene5 week mindful-music listening intervention including sleep hygiene
Primary Outcome Measures
NameTimeMethod
Sleep onset latency (SOL)Measured daily, from baseline to follow-up (day 1 up to day day 71).

Time taken to fall asleep in minutes measured using actigraphy and a sleep diary completed by the participant. Higher scores indicate greater SOL.

Secondary Outcome Measures
NameTimeMethod
Total sleep time (TST)Measured daily, from baseline to follow-up (day 1 up to day day 71).

Total time spent asleep in bed in minutes. Measured using actigraphy and a sleep diary completed by the participant. Higher scores indicated longer time spent asleep.

Wake after sleep onset (WASO)Measured daily, from baseline to follow-up (day 1 up to day day 71).

Total time spent awake after sleep onset in minutes. Measured using actigraphy and a sleep diary completed by the participant. Higher scores indicate longer time spent awake.

Number of night time awakeningsMeasured daily, from baseline to follow-up (day 1 up to day day 71).

Total number of awakenings during the night. Measured using actigraphy and a sleep diary completed by the participant. Min = 0 - no Max. Lower scores indicate fewer night time awakenings.

Time in bed (TIB)Measured daily, from baseline to follow-up (day 1 up to day day 71).

Total time spent in bed in minutes with higher scores indicating longer time spent in bed. Measured using a sleep diary completed by the participant.

Sleep restorationMeasured daily, from baseline to follow-up (day 1 up to day day 71).

Participant rated level of sleep restoration on awakening. Measured using a 3-point scale: refreshed, somewhat refreshed, fatigued.

Insomnia classificationCompleted at baseline, end of intervention (week 1 to weeks 6-8 and at follow up (3 weeks post-intervention)

Sleep Condition Indicator (SCI) score. Min score= 0 - Max= 32 with lower scores indicating poorer sleep.

Daytime sleepinessCompleted at baseline, at the end of intervention (week 1 to weeks 6-8) and at follow-up (3 weeks post-intervention)

Epworth Sleepiness Scale (ESS) score. Min score= 0 - Max= 24 with higher scores indicating greater levels of daytime sleepiness.

Anxiety symptomsCompleted at baseline, end of intervention (week 1 to weeks 6-8 and at follow up (3 weeks post-intervention)

Generalized Anxiety Disorder Questionnaire (GAD-7) score. Min= 0 - Max= 21 with higher scores indicating more severe symptoms.

Depressive symptomsCompleted at baseline, end of intervention (week 1 to weeks 6-8 and at follow up (3 weeks post-intervention)

Patient Health Questionnaire (PhQ-9) score. Min= 0 - Max= 27 with higher scores indicating more severe symptoms.

FatigueCompleted at baseline, end of intervention (week 1 to weeks 6-8 and at follow up (3 weeks post-intervention)

Fatigue Severity Scale (FSS) score. Min= 9 - Max= 63 with higher scores indicating greater fatigue severity.

AdherenceCompleted daily by the participant during the intervention music listening phase (weeks 3-5 to weeks 8-10)

Adherence to mindful music-listening as measured through music listening diary. Min= 0 - Max= 28 with higher scores indicating greater adherence.

Trial Locations

Locations (1)

Greater Glasgow and Clyde Stroke Services

🇬🇧

Glasgow, United Kingdom

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