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临床试验/NCT05091398
NCT05091398已完成不适用

Erector Spinae Plane, Paravertebral Versus Intercostal Nerve Block for VATS Surgery

Tanta University1 个研究点 分布在 1 个国家目标入组 105 人开始时间: 2021年11月5日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
105
试验地点
1
主要终点
end tidal sevoflurane

研究概览

简要总结

The optimal analgesia method in video-assisted thoracoscopic surgery (VATS) remains controversial. 105 patients scheduled to undergo video-assisted thoracic surgery under general anesthesia will be included. Patients will be randomly allocated to receive ultrasound-guided ESP blocks on T4 and T6 levels (Group ESPB, n = 35),PVB (Group PVB, n = 35) after the anesthesia induction and turning the patient in the lateral position or (Group ICNB, n=35) with 30 mL 0.5% bupivacaine +50 µ adrenaline will be injected by the surgeon through the thoracoscope .

详细描述

Standard general anesthesia was applied Patients will be randomly allocated to receive single shot of ESP blocks (Group ESPB), Paravertebral blocks (Group PVB) or (Group ICNB )at T4 and T6 levels according to a random number list that will be generated by a computer and will be stored in sealed envelopes. An independent experienced anesthesiologist will perform the first two blocks or surgeon will perform the third one through the thoracoscope according to the random number. The study coordinator, attending anesthesiologist, data collection resident and the patients will be all blinded to the treatment group assignment. All blocks will be applied on patient's back in a lateral position. Postoperative analgesia regimen consisted of a continuous infusion of iv iboprofen and morphine as a second rescue drug. Demographic data, past medical history, surgical and anesthetic data will be documented. Postoperative pain scores, consumption of analgesia and quality of recovery will be recorded to evaluate the analgesic effect.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Other
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •ASA I and II patients
  • •Thoracic surgery

排除标准

  • •Coagulation defect

研究组 & 干预措施

Group I

Active Comparator

ultrasound-guided erector spinae block on T4 and T6 levels after the anesthesia induction and turning the patient in the lateral position

干预措施: Regional analgesia of thoracic surgical patients (Other)

Group II

Active Comparator

ultrasound-guided paravertebral block on T4 and T6 levels after the anesthesia induction and turning the patient in the lateral position

干预措施: Regional analgesia of thoracic surgical patients (Other)

Group III

Active Comparator

ultrasound-guided intercostal nerve block on T4 and T6 levels after the anesthesia induction and turning the patient in the lateral position

干预措施: Regional analgesia of thoracic surgical patients (Other)

结局指标

主要结局

end tidal sevoflurane

时间窗: 150 minutes

intraoperative end tidal sevoflurane

次要结局

  • Blood pressure(150 minutes)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mona Mohamed Mogahed

Associate professor

Tanta University

研究点 (1)

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