The Prognostic Value of the Time From Onset of Fever to Administration of Antibiotics in Neutropenic Fever Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 315
- 试验地点
- 1
- 主要终点
- 14 day cause specific mortality rate
研究概览
简要总结
This trial uses an interview and a survey to gather information from cancer patients about the onset of their fever and the administration of antibiotics. Collecting information from patients may help doctors to assess the relationship between time to antibiotic administration and inhospital cause specific death, intensive care unit admission, hospital length of stay, and positive blood cultures.
详细描述
PRIMARY OBJECTIVES:
I. To assess the prognostic value of the length of time between the time onset of fever and first antibiotic administration on cause specific 14 day mortality rate.
SECONDARY OBJECTIVES:
I. To assess the associations of the length of time between the time onset of fever and first antibiotic administration with intensive care unit (ICU) admission, ICU length of stay, length of hospitalization and percentage of patients with positive blood cultures.
OUTLINE:
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
14 day cause specific mortality rate
时间窗: At 14 days
Will perform univariate logistic regression analysis to assess the effect of time to antibiotic administration on death 14 days post fever onset. Will build multivariate logistic regression model(s) to further assess the effect of time to antibiotic administration on death 14 days post fever onset adjusting for other potential confounders.
次要结局
- ICU length of stay(Up to 5 years)
- Cause specific death(Up to 5 years)
- Intensive care unit (ICU) admission rate(Up to 5 years)
- Length of hospitalization(Up to 5 years)
- Percentage of patients with positive blood cultures(Up to 5 years)