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Effect of 2000-meter Rowing Test on Parameters of Intestinal Integrity in Elite Rowers During Competitive Phase

Completed
Conditions
Endothelial Dysfunction
Registration Number
NCT06372262
Lead Sponsor
Poznan University of Physical Education
Brief Summary

The study aimed to check the 2000m ergometer test on markers of gut permeability in the competitive phase of rowers. 18 members of the Polish rowing team took part in the study.

Detailed Description

The phenomenon of epithelial wall leakage has been the subject of investigations within athletic domains such as running and cycling. Nevertheless, there exists an insufficiency of understanding regarding gut permeability in alternative disciplines, such as rowing, particularly following the completion of a standard competitive distance of 2000 meters. Hence, the principal objective of our study was to assess gut permeability after completing a 2000-meter rowing test. The study was performed at the beginning of a competitive training phase. Eighteen elite Polish Rowing Team rowers participated in the study after applying the inclusion/exclusion criteria. The participants performed a 2000-meter ergometer test. Blood samples were taken before the test, after exercise, and after 1-hour of restitution. Parameters, such as I-FABP, LPS, LBP, and zonulin, were determined using appropriate biochemical tests.

Recruitment & Eligibility

Status
COMPLETED
Sex
Male
Target Recruitment
18
Inclusion Criteria
  • minimum five years of training,
  • five training sessions per week minimum,
  • total training time minimum of 240 minutes,
  • membership in the Polish Rowing Team,
  • finishing the 2000-meter ergometer test.
Exclusion Criteria
  • antibiotic therapy within the last three months,
  • probiotics and prebiotics within the last three months,
  • dietary regime,
  • gastrointestinal diseases.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
LBP (lipopolysaccharide binding protein) to measure endotoxinBlood samples was taken from the cubital vein at three-time points: before each stress test (after overnight fasting), one minute after the end of the test, and after a 1-hour recovery period

LBP concentration measured in blood \[ug/ml\] using commercially available enzyme-linked immunosorbent assays

LPS (lipopolysaccharide) to measure endotoxinBlood samples was taken from the cubital vein at three-time points: before each stress test (after overnight fasting), one minute after the end of the test, and after a 1-hour recovery period

LPS concentration measured in blood \[EU/Ll\] using commercially available enzyme-linked immunosorbent assays

zonulin to measure tight junction leakageBlood samples was taken from the cubital vein at three-time points: before each stress test (after overnight fasting), one minute after the end of the test, and after a 1-hour recovery period

zonulin concentration measured in blood \[ng/ml\] using commercially available enzyme-linked immunosorbent assays

Lactic acid to measure fatigue after the raceBlood samples was taken from earlobe at two-time points: before each stress test (after overnight fasting), one minute after the end of the test.

Lactate concentration measured in capillary blood from earlobe \[mmol/L\] using a commercially available kit (Diaglobal, Berlin, Germany)

I-FABP (intestinal fatty acid binding protein)to measure epithelial wall injuryBlood samples was taken from the cubital vein at three-time points: before each stress test (after overnight fasting), one minute after the end of the test, and after a 1-hour recovery period

I-FABP concentration measured in blood \[ng/ml\] using commercially available enzyme-linked immunosorbent assays

Secondary Outcome Measures
NameTimeMethod
fiber intakeday before test

fiber \[g\] intake day before the test measured by 24h dietary recall

proteinday before test

protein \[g\] intake day before the test measured by 24h dietary recall

Lean body massin the morning before the test

Lean body mass \[kg\] measured by electronic scale (Tanita BC 418 MA Tanita Corporation, Tokyo, Japan).

energyday before test

energy \[kcal \]of food intake measured by 24h dietary recall

carbohydrateday before test

carbohydrate \[g\] intake day before the test measured by 24h dietary recall

body massin the morning before the test

Body mass \[kg\] measured by electronic scale to the nearest 0,05 kg (Tanita BC 418 MA Tanita Corporation, Tokyo, Japan).

Body composition - fatin the morning before the test

% of body fat measured by electronic scale (Tanita BC 418 MA Tanita Corporation, Tokyo, Japan).

Body composition - waterin the morning before the test

% of body water measured by electronic scale (Tanita BC 418 MA Tanita Corporation, Tokyo, Japan).

Trial Locations

Locations (1)

Poznan University of Physical Education

🇵🇱

Poznań, Poland

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