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临床试验/NCT06484387
NCT06484387招募中不适用

Study of Multimodal Intra- and Interpersonal Synchronizations in Social Interaction in Individuals with a Diagnosis of Schizophrenia.

University Hospital, Montpellier1 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2024年11月8日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
招募中
入组人数
120
试验地点
1
主要终点
interpersonal synchronization

研究概览

简要总结

The aim of this study is to precisely identify deficits in intra- and interpersonal multimodal synchronizations during social interaction in individuals with schizophrenia (ISZ). During a social interaction, individuals use both visual and auditory channels to construct their discourse. The auditory channel encompasses the semantics and prosody of the speech, while the visual channel describes the entirety of non-verbal gestures (e.g., facial expressions, body movements). Prosody and non-verbal gestures are essential elements for the speaker. By accompanying speech, they contribute to the planning and conceptualization of the utterance and enhance its communicative power. For the listener, prosody and non-verbal gestures are also used to provide sensory feedback to the speaker.

Several studies have shown the existence of intrapersonal and interpersonal synchronizations of prosody and non-verbal gestures during interaction. These synchronizations are associated with numerous social benefits (e.g., increased mutual appreciation and quality of interaction). However, certain mental disorders, such as schizophrenia, exhibit deficits in non-verbal behaviors that can impair these synchronizations and the associated social benefits. We hypothetized that interaction with individuals with a daignosis of schizophrenia will be associated with deficits in intra and interpersonal synchronization.

详细描述

This study includes a pre-inclusion interview followed by a visit to the university hospital (CHU) lasting about 2 hours (including a break). During the visit, the patient participates in an experimental protocol consisting of two parts. In the first part, the patient will be paired with an interaction partner, and the two participants will engage in four distinct conversational tasks, including getting to know each other, free discussions, structured dialogues, and emotional interactions. In the second part, the participants will answer several questionnaires and perform neuropsychological tests in collaboration with an experimenter

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Individuals with a diagnosis of schizophrenia :
  • •Inclusion Criteria:
  • •diagnosis of schizophrenia according to the DSM-V
  • •being able to read, speak and understand french
  • •giving eclaired consent

排除标准

  • •history of head trauma
  • •history of neurological conditions (epilespsy, multiple sclerosis, parkinson's disease, amyotrophic lateral sclerosis, huntington's disease, stroke)
  • •substance use
  • •pregnant women
  • •Healthy controls :
  • •Inclusion Criteria:
  • •being able to read, speak and understand french
  • •giving eclaired consent
  • •Exclusion Criteria:
  • •diagnosis of psychosis
  • •history of head trauma
  • •history of neurological conditions (epilespsy, multiple sclerosis, parkinson's disease, amyotrophic lateral sclerosis, huntington's disease, stroke)
  • •substance use
  • •pregnant women

研究组 & 干预措施

dyad schizophrenia and interacting partner

Experimental

social interaction between an individual with a diagnosis of schizophrenia and his interacting partner

干预措施: Social interaction (Behavioral)

dyad healthy subject and interacting partner

Experimental

social interaction between a healthy subject and his interacting partner

干预措施: Social interaction (Behavioral)

结局指标

主要结局

interpersonal synchronization

时间窗: 4x6 minutes

synchronization between body movements of two interacting partners

intrapersonal synchronization

时间窗: 4x6 minutes

synchronization between voice and body movements of one individual

次要结局

  • correlation between primary outcomes and individuals with schizophrenia medications(4x6 minutes)
  • correlation between synchronization and willingness to continue the interaction(4x6 minutes)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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