DROP-Benzo (De-adopting Routine Preoperative Benzodiazepines for Older Surgical Patients): a Randomized Trial of Behavioral Strategies to Reduce Unnecessary Midazolam Administration to Older Surgical Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 517,611
- 试验地点
- 1
- 主要终点
- Benzodiazepine administration rate
研究概览
简要总结
Over 21 million surgical procedures take place among adults aged 65 and older in the US each year, and most older surgical patients in the US now receive benzodiazepines (e.g., midazolam, lorazepam) during anesthesia care. This occurs despite recommendations to avoid these medications in older patients due to associated medical risks and lack of demonstrated benefit. In other words, routine benzodiazepine administration to older surgical patients is likely to represent low-value care that is a suitable target for de-adoption. In this study, we will evaluate a United States Anesthesia Partners (USAP, Dallas, TX) quality improvement initiative using peer comparison feedback to clinicians and/or mailed informational letters to patients as strategies to encourage physician de-adoption of routine preoperative benzodiazepine administration to older surgical patients. In partnership with USAP, this study will be conducted using randomization to evaluate its effect.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 65 Years 至 —(Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All anesthesia clinicians employed by USAP will be included in the evaluation. Patients will be included if they are at least aged 65 and undergo an elective (scheduled) surgical or endoscopic procedure under general anesthesia.
排除标准
- •Patients will be excluded if they are unscheduled (urgent/emergent) cases due to inability to reliably deliver study interventions to this group; if they did not receive general anesthesia; or if they received a nerve block procedure.
研究组 & 干预措施
Peer Comparison Feedback
干预措施: Peer Comparison Feedback (Behavioral)
Patient Informational Letter
干预措施: Patient Informational Letter (Behavioral)
Peer Comparison Feedback plus Patient Informational Letter
干预措施: Peer Comparison Feedback (Behavioral)
Peer Comparison Feedback plus Patient Informational Letter
干预措施: Patient Informational Letter (Behavioral)
Control
结局指标
主要结局
Benzodiazepine administration rate
时间窗: Intraoperative period
The primary outcome measure is the change in the rate of benzodiazepine administration among eligible surgical cases.
次要结局
- Patient satisfaction(Up to 30 days after surgery)
研究者
Mark Neuman
Associate Professor
University of Pennsylvania
