跳至主要内容
临床试验/NCT05436392
NCT05436392已完成不适用

DROP-Benzo (De-adopting Routine Preoperative Benzodiazepines for Older Surgical Patients): a Randomized Trial of Behavioral Strategies to Reduce Unnecessary Midazolam Administration to Older Surgical Patients

University of Pennsylvania1 个研究点 分布在 1 个国家目标入组 517,611 人开始时间: 2022年8月8日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
517,611
试验地点
1
主要终点
Benzodiazepine administration rate

研究概览

简要总结

Over 21 million surgical procedures take place among adults aged 65 and older in the US each year, and most older surgical patients in the US now receive benzodiazepines (e.g., midazolam, lorazepam) during anesthesia care. This occurs despite recommendations to avoid these medications in older patients due to associated medical risks and lack of demonstrated benefit. In other words, routine benzodiazepine administration to older surgical patients is likely to represent low-value care that is a suitable target for de-adoption. In this study, we will evaluate a United States Anesthesia Partners (USAP, Dallas, TX) quality improvement initiative using peer comparison feedback to clinicians and/or mailed informational letters to patients as strategies to encourage physician de-adoption of routine preoperative benzodiazepine administration to older surgical patients. In partnership with USAP, this study will be conducted using randomization to evaluate its effect.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Factorial
主要目的
Health Services Research
盲法
None

入排标准

年龄范围
65 Years 至 —(Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •All anesthesia clinicians employed by USAP will be included in the evaluation. Patients will be included if they are at least aged 65 and undergo an elective (scheduled) surgical or endoscopic procedure under general anesthesia.

排除标准

  • •Patients will be excluded if they are unscheduled (urgent/emergent) cases due to inability to reliably deliver study interventions to this group; if they did not receive general anesthesia; or if they received a nerve block procedure.

研究组 & 干预措施

Peer Comparison Feedback

Experimental

干预措施: Peer Comparison Feedback (Behavioral)

Patient Informational Letter

Experimental

干预措施: Patient Informational Letter (Behavioral)

Peer Comparison Feedback plus Patient Informational Letter

Experimental

干预措施: Peer Comparison Feedback (Behavioral)

Peer Comparison Feedback plus Patient Informational Letter

Experimental

干预措施: Patient Informational Letter (Behavioral)

Control

No Intervention

结局指标

主要结局

Benzodiazepine administration rate

时间窗: Intraoperative period

The primary outcome measure is the change in the rate of benzodiazepine administration among eligible surgical cases.

次要结局

  • Patient satisfaction(Up to 30 days after surgery)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mark Neuman

Associate Professor

University of Pennsylvania

研究点 (1)

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