The Role of Puberty and Insulin Resistance in the Development of Hyperglucagonemia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 83
- 试验地点
- 1
- 主要终点
- Overweight and Lean Children Sugar Metabolism Before and During Puberty
研究概览
简要总结
Our goal is to investigate how hormones that control blood sugar, hunger, and stomach emptying change with puberty and being overweight. These substances change with a meal.
- For this, we need to compare lean and overweight children.
- We need to study them before and during puberty.
- All children in the study will be tested before and after a liquid meal.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 8 Years 至 17 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •All groups:
- •Healthy lean and otherwise healthy overweight children and adolescents between the ages of 8 and 17.
排除标准
- •Same for all groups
- •The subjects will be excluded if they have:
- •a history of chronic disease
- •allergy to acetaminophen
- •evidence or history of chemical abuse
- •abnormal lab values
- •pregnancy
结局指标
主要结局
Overweight and Lean Children Sugar Metabolism Before and During Puberty
时间窗: 4 hours
Too much weight gain can cause changes in the substances that control blood sugar and hunger in the body. Scientists need to compare these substances in lean and overweight children before and during puberty. These substances can be measured before and after a meal in the blood and in the urine. The way your stomach moves food can change your sugar levels. We want to understand how diabetes develops by studying these things. This can help find better ways to prevent and treat diabetes.
次要结局
未报告次要终点
研究者
Luisa M. Rodriguez
The Role of Puberty and Insulin Resistance in the Development of Hyperglucagonemia
Baylor College of Medicine