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The Effects of Puberty and Weight on Sugar Metabolism in Children

Completed
Conditions
Leanness
Adolescent
Overweight
Registration Number
NCT01718080
Lead Sponsor
Baylor College of Medicine
Brief Summary

Our goal is to investigate how hormones that control blood sugar, hunger, and stomach emptying change with puberty and being overweight. These substances change with a meal.

* For this, we need to compare lean and overweight children.

* We need to study them before and during puberty.

* All children in the study will be tested before and after a liquid meal.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
83
Inclusion Criteria

All groups:

Healthy lean and otherwise healthy overweight children and adolescents between the ages of 8 and 17.

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Exclusion Criteria

Same for all groups

The subjects will be excluded if they have:

  • a history of chronic disease
  • allergy to acetaminophen
  • evidence or history of chemical abuse
  • abnormal lab values
  • pregnancy
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Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Overweight and Lean Children Sugar Metabolism Before and During Puberty4 hours

Too much weight gain can cause changes in the substances that control blood sugar and hunger in the body. Scientists need to compare these substances in lean and overweight children before and during puberty. These substances can be measured before and after a meal in the blood and in the urine. The way your stomach moves food can change your sugar levels. We want to understand how diabetes develops by studying these things. This can help find better ways to prevent and treat diabetes.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Baylor College of Medicine

🇺🇸

Houston, Texas, United States

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