NL-OMON43505
Completed
Not Applicable
INeS Follow-up;Medically assisted reproduction techniques: do they influence the offspring*s growth, health and neurodevelopment? Follow-up of a randomized controlled trial - INeS Follow-up
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- cardiovasculaire gezondheid, metabolde gezondheid, groei, neurodevelopment
- Sponsor
- Academisch Medisch Centrum
- Enrollment
- 354
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •The study population comprises all children born to couples who participated in the INeS\-study (registered as NL12782\.018\.07, METC 2007\_064\). The INeS\-study consisted of couples seeking fertility treatment after at least 12 months of unprotected intercourse. Females were between 18 and 38 years of age and had an unfavorable prognosis for natural conception (less than 30% according to the Hunault model). Couples were diagnosed with an unexplained or mild subfertility. Couples were excluded in case of polycystic ovarian syndrome (PCOS)/anovulation, endometriosis, bilateral tubal pathology or endocrine disorders. 602 Couples were randomly allocated to three cycles of IVF\-SET, six cycles of IVF\-MNC or six cycles of IUI\-COH. ;There were 354 children born in the INeS\-study: 313 singletons, 19 twins and 1 triplet. These children were born during the 12 month follow\-up period (n\<\=333\) or somewhat thereafter (n\<\=9\).
Exclusion Criteria
- •There are no exclusion criteria.
Outcomes
Primary Outcomes
Not specified
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