Hyperbaric Oxygen Therapy and SPECT Brain Imaging in Cerebral Decompression Illness
试验速览
- 阶段
- 1 期
- 发起方
- 入组人数
- 45
- 试验地点
- 1
- 主要终点
- SPECT brain imaging
研究概览
简要总结
Chart review of patients who received hyperbaric oxygen therapy for cerebral decompression illness who also underwent SPECT brain blood flow imaging to see if SPECT brain imaging tracks and is consistent with the clinical condition of the patients.
详细描述
SPECT brain imaging has been shown to be the most sensitive imaging modality for cerebral decompression illness. This study is a retrospective review of the PI's experience using SPECT brain imaging in the diagnosis and treatment of all phases of cerebral decompression illness over the past two decades. The purpose of the study is to see if the functional imaging is consistent with the clinical condition and cognitive testing. Chart review of symptoms, and physical exam findings will be compared before and after treatment to SPECT brain imaging radiological readings to assess concordance.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients in the P.I.'s practice who underwent hyperbaric oxygen therapy for cerebral decompression illness in the previous two decades who also underwent SPECT brain blood flow imaging early in the course of treatment and following completion of hyperbaric oxygen therapy.
排除标准
- 未提供
研究组 & 干预措施
Hyperbaric oxygen therapy
Hyperbaric oxygen therapy
干预措施: Hyperbaric oxygen therapy (Drug)
结局指标
主要结局
SPECT brain imaging
时间窗: Within one month after completion of hyperbaric oxygen therapy
Comparison of SPECT brain imaging chart copy of radiological reading before or early in the treatment history to SPECT brain imaging chart copy of radiological reading after treatment. Imaging will be scored as better, worse, or no change based on resolution of defects or improvement in pattern of injury.
次要结局
- Symptoms of cerebral decompression illness(Within one month after hyperbaric oxygen therapy)
- Abnormal physical exam findings(Within one month after hyperbaric oxygen therapy)
研究者
Paul G. Harch, M.D.
Clinical Professor of Medicine
Louisiana State University Health Sciences Center in New Orleans