A Randomised controlled single blinded trial to compare Opioid free anesthesia and Opioid based anesthesia in patients undergoing elective craniotomy for Supratentorial lesion
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 64
- 试验地点
- 1
- 主要终点
- To compare duration to first rescue analgesic requirement in post operative period in
研究概览
简要总结
this study was formulated to assess the utility and efficacy of opioid
based and opioid free anesthesia in patients undergoing craniotomy for supratentorial lesions . Aim of the study is to compare the opioid free anesthesia technique to conventional opioid based
technique in patients undergoing supratentorial craniotomy in patients for rescue analgesic
requirement and pain scores
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patient belonging to ASA I,II,III Patients with pre operative GCS more than 14 Patient posted for elective supratentorial lesion.
排除标准
- •Patient posted for emergency craniotomy surgeries 3) Patient belonging to ASA IV and above 4) Patient with bradycardia (Heart rate <60 beats per minute) 5) Patient refusing to consent 6) Patient with chronic pain or on opioid medication 7) Patient with known allergy to study drugs 8) Patients with difficult airway.
结局指标
主要结局
To compare duration to first rescue analgesic requirement in post operative period in
时间窗: To compare duration to first rescue analgesic requirement in post operative period in | patients undergoing supratentorial craniotomy receiving opioid based anesthesia and | those receiving opioid free anesthesia
patients undergoing supratentorial craniotomy receiving opioid based anesthesia and
时间窗: To compare duration to first rescue analgesic requirement in post operative period in | patients undergoing supratentorial craniotomy receiving opioid based anesthesia and | those receiving opioid free anesthesia
those receiving opioid free anesthesia
时间窗: To compare duration to first rescue analgesic requirement in post operative period in | patients undergoing supratentorial craniotomy receiving opioid based anesthesia and | those receiving opioid free anesthesia
次要结局
- post operative pain at 1,2,4,6,12 and 24 hours post operatively.(at 1,2,4,6,12 and 24 hours post operatively.)
- total dose of rescue analgesic(post operatively.)
- incidence of side effects like bradycardia, tachycardia, hypotension ,(hypertension, post operative nausea vomiting , pruritus, respiratory depression)
- total number of propofol bolus(intra operatively.)
- compare quality of recovery (QoR- 15) score(at 1, 6 ,12 , 24 hours post operatively)
研究者
Bishnupriya Mohapatra
AIIMS Rishikesh