Comparison of the Effectiveness of Bupivacaine and Bupivacaine+Dexmedetomidine Combination in Transversus Abdominis Plane* Block in Colorectal Cancer Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Bupivacain
- Conditions
- Colorectal Cancer
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
- Enrollment
- 84
- Locations
- 1
- Primary Endpoint
- Analgesic effectiveness of bupivacain and bupivacain+dexmedetomidine combination in colorectal cancer surgery
- Status
- Not yet recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
Transversus abdominis plane (TAP) block is an anesthesia method that provides somatic analgesia to the anterior and lateral abdominal walls. Thus, TAP block is widely implemented in perioperative management of colorectal cancer patients.
Researchers aimed to evaluate the analgesic effectiveness and duration of effect of dexmedetomidine added to bupivacaine in the TAP block applied in colorectal cancer surgeries.
Detailed Description
Transversus abdominis plane (TAP) block is an anesthesia method that provides somatic analgesia to the anterior and lateral abdominal walls. With the increasing use of ultrasound guidance during peripheral nerve blocks, trunk blocks such as the transversus abdominis plane (TAP) block are widely used for analgesia after abdominal surgery. The advantages of TAP block include being less invasive than epidural analgesia, lower incidence of hypotension, and shorter hospital stay. Due to these advantages, TAP block has become a widely preferred method. Researchers aimed to evaluate the analgesic effectiveness and duration of effect of dexmedetomidine added to bupivacaine in the TAP block applied in colorectal cancer surgeries. The study will be conducted in a tertiary oncology hospital in Turkey and 84 colorectal cancer patients will be included.
Investigators
Beyza Seker
Resident Anaesthesiologist
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Eligibility Criteria
Inclusion Criteria
- •colorectal cancer diagnosis
- •undergoing colorectal cancer surgery
Exclusion Criteria
- •allergic reaction to local anesthetics
- •bleeding anomalies
- •infection in TAP block area
Arms & Interventions
bupivacaine
Ultrasonography (USG) guided bilateral TAP block:20 ml %0,25 concentration bupivacain
Intervention: Bupivacain
bupivacaine+dexmedetomidine
Ultrasonography (USG) guided bilateral TAP block: 20 ml %0,25 concentration bupivacain+ 0.5 mcg/kg dexmedetomidine
Intervention: bupivacain+dexmedetomidine
Outcomes
Primary Outcomes
Analgesic effectiveness of bupivacain and bupivacain+dexmedetomidine combination in colorectal cancer surgery
Time Frame: postoperative day two
Numeric Rating Scales of two groups in postoperative period. The numeric rating scale (NRS) is a pain screening tool, commonly used to assess pain severity at that moment in time using a 0-10 scale, with zero meaning "no pain" and 10 meaning "the worst pain imaginable"