Therapeutic efficacy of intense pulsed light for treatment of meibomian gland dysfunction in glaucoma patients
- Conditions
- Treatment of meibomian gland dysfunction in glaucoma patients.intense pulsed light,meibomian gland dysfunction,glaucoma
- Registration Number
- TCTR20200709006
- Lead Sponsor
- Faculty of Medicine Siriraj Hospital, Mahidol University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Active, not recruiting
- Sex
- All
- Target Recruitment
- 70
Glaucoma patients treated with 1 or more eye drops that have MGD with more than or equal to 2 items as follows
1. redness or thickening lid margin
2. Telangiectasia
3. reduced secretions of meibum or poor quality secretion of meibum
4. Meibomian gland loss
5. abnormal tear break-up time (TBUT)
1. there are other diseases of the eyelids and cornea.
2. have a congenital disease affecting the eyes.
3. having a history of corneal transplantation or glaucoma surgery.
4. have been punctual occlusion to treat dry eye before.
5. use eye drops that regularly affect the cornea, including antibiotics and anti-inflammatory drugs.
6. use the following drugs regularly: hormones that treat menopause symptoms (Estrogen, Progestin), Antihistamine, Anti-anxiety disorder and Tricyclic antidepressant, Retinoids
7. light allergies, facial herpes and epilepsy.
8. unable to cooperate with the examination with a slit lamp biomicroscopy and using an IPL
9. people with severe side effects from IPL lasers such as skin colour change that can be noticeable, allergic rash or scarring.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Ocular surface symptom Visit 0, day15, day30, day45, day60, day75 Ocular surface symptom questionnaire,Ocular surface symptom Visit 0, day15, day30, day45, day60, day75 Ocular surface symptom questionnaire
- Secondary Outcome Measures
Name Time Method Tear osmolality Visit 0, day75 Tear osmolality test card