The effect of propolis dietary supplement on the status of hs-CRP inflammatory index, sex hormone testosterone levels and metabolic profile of women with polycystic ovary syndrome

Phase 3

• Conditions: Polycystic ovarian syndrome.; Polycystic ovarian syndrome; E28.2

• Registration Number: IRCT20121216011763N51
• Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 29 August 2022

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 56

Inclusion Criteria

Diagnosis of PCOS according to Rotterdam criterion: According to this criterion, the subjects should have two of the three diagnostic features of PCOS: 1- Oligomenorrhea and anovulation 2- Hyperandrogenism 3- Polycystic ovary
Age between 18 and 45 years
Not to have sensitivity to bee products
Not to take any specific drug more than metformin
Not to have laparoscopic ovarian surgery and assisted reproductive technology

Exclusion Criteria

Hormone therapy or taking contraceptive pills (OCP)
History of gestational hypertension
Pregnancy or breastfeeding
Menopause
Tobacco and alcohol consumption
Having following diseases: Diabetes, cardiovascular, hepatic, renal, thyroid, asthma, neoplasm

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Homeostatic model assessment of insulin resistance (HOMA-IR). Timepoint: Before study and 12 weeks after supplementation. Method of measurement: formula= (fasting plasma glucose(mmol/l) *fasting insulin (IU/ml))/22.5.