ACTRN12617001560381终止未知
Circulating Tumour DNA Analysis Informing Adjuvant Chemotherapy in Locally Advanced Rectal Cancer: A Multicentre Randomised Study (DYNAMIC-RECTAL)
AGITG0 个研究点目标入组 250 人开始时间: 2017年11月15日最近更新:
试验速览
- 阶段
- 未知
- 状态
- 终止
- 发起方
- 入组人数
- 250
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •1.Aged 18 years of age and over
- •2.Subjects with locally advanced rectal cancer treated with curative intent
- •3.Subjects treated with pre-operative long course chemo-radiation and surgery
- •4.CT scan of chest/abdomen/pelvis prior to commencing pre-operative chemo-radiation demonstrating no metastatic disease
- •5.A tumour sample (from the pre-treatment biopsy or surgery specimen is available for molecular testing within 35 days after surgery
- •6.Fit for adjuvant (post surgery) chemotherapy
排除标准
- •1.History of another primary cancer within the last 3 years (with the exception of non-melanoma skin cancer and carcinoma in situ).
- •2.Patients with multiple primary colorectal cancers
- •3.Inadequate bone marrow, kidney and liver function, as determined by blood tests
- •4.Evidence of active infection
- •5.Clinically significant cardiovascular disease
- •6.Medical or psychiatric condition or occupational responsibilities that may preclude compliance with the study requirements
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